태음조위탕이 비만유발 흰쥐의 체중감량, 혈청지질 및 UCP1 발현에 미치는 영향

Effects of Taeyeumjowee-tang on Loss in Body Weight, Plasma Lipids and UCP I Revelation of Fated White Rats

  • 조세왕 (동국대학교 한의과대학 사상체질과) ;
  • 방성식 (동국대학교 한의과대학 사상체질과)
  • 발행 : 2004.06.01

초록

Objectives : To identify the effect of Taeyeumjowee-tang on the treatment of obesity Methods : After having been fed a high-fat diet for 6 weeks, obese white rats were classified into three groups. Control group 1 was fed a high-fat diet for 2 more weeks. Control group 2 was fed a normal diet for 2 weeks. The Sample group was fed Taeyeumjowee-tang extract with a normal diet for 2 weeks. The result of the comparison among the three groups was as follows. Results : The Sample group decreased significantly as compared with the Control 1 and 2 groups in changes of the body weight, fat cell size, fat accumulation, insulin, triglyceride, total cholesterol, total lipid, free fatty acid and UCP1. Conclusions : Taeyeumjowee-tang has significant effect on the treatment of obesity resulting from a high-fat diet. Especially, it was a sure remedy for Control group 2 that was fed normal1y after having a high-fat diet.

키워드

참고문헌

  1. Nature v.404 no.6778 Obesity as a problem Peter G. Kopelman
  2. 임상내분비학 초판 민헌기
  3. 四象醫學會誌 v.3 no.1 太陰人 남학생의 혈액변화에 대한 연구 김경요;한종현;홍순용
  4. 四象醫學會誌 v.5 no.1 체질별 혈청脂質성분의 분석에 관한 실험적 고찰 김경준;김달래
  5. 한방재활의학회지 v.7 no.2 비만환자에서의 태소음양인의 분포 배정환;신현대
  6. 東醫壽世保元 이제마
  7. 四象醫學 전국한의과대학 사상의학회
  8. 東武遺稿(國譯漢醫學大系 15) 량병무;차광석(번역);이제마(저)
  9. 太陰調胃湯이 흰쥐의 비만증 및 유도비만세포에 미치는 효과 이기주
  10. 太陰調胃湯 加 麻黃이 생쥐의 비만변인에 미치는 영향 김유성
  11. 太陰調胃湯과 麻黃이 비만 흰쥐의 Leptin에 미치는 영향 신동준
  12. 四象藥方의 特徵과 形成過程에 대한 연구 배효상
  13. 四象體質 유형과 체격 및 신체형태지수와의 비교연구 이문호
  14. 비만에 대한 문헌적 고찰 변진우
  15. 사상의학회지 v.6 no.1 동의수세보원 사상인 표리병증 편명에 대한 소고 박성식
  16. 申氏本草學 신길구
  17. 東醫四象新編(국역한의학대계13권) 원덕필
  18. 東醫四象大典 박석언
  19. 四象醫學原論 이을호;홍순용
  20. Cell v.87 no.3 Adipogenesis and obesity: rounding out the big picture Spiegelman BM;Flier JS
  21. Scand J Gastroenterol. v.35 no.9 Fatty liver in obesity: relation to Doppler perfusion index measurement of the liver Kakkos SK;Yarmenitis SD;Tsamandas AC;Gogos CA;Kalfarentzos F
  22. J Clin Endocrinol Metab. v.87 no.7 Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in Normal men Seppala-Lindroos A;Vehkavaara S;Hakkinen AM;Goto T;Westerbacka J;Sovijarvi A;Halavaara J;Yki-Jarvinen H
  23. Am J Clin Nutr. v.78 no.4 Suppl. 2 Sugars, hypertriglyceridemia, and cardiovascular disease Fried SK;Rao SP
  24. Adv Exp Med Biol. v.441 Regulation of fatty acid delivery in vivo Frayn KN
  25. Reprod Nutr Dev. v.36 no.4 Nutritional and metabolic aspects of postprandial lipemia Lairon D.
  26. Front Biosci. v.6 Lipoprotein lipase: physiology, biochemistry, and molecular biology Goldberg IJ;Merkel M
  27. Nutrition v.12 no.6 Influence of nutrition on liver oxidative metabolism Jorquera F;Culebras JM;Gonzalez-Gallego J
  28. J Nucl Cardiol. v.9 no.6 The physiology of lipoproteins Tulenko TN;Sumner AE
  29. JOGN Nurs. v.9 no.6 The structure and function of brown adipose tissue in the neonate Davis V.
  30. Diabetologia v.44 Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes Dalgaard LT;Pederson O
  31. J Appl Physiol. v.92 no.5 Uncoupling proteins and thermoregulation Argyropoulos G;Harper ME
  32. Nature v.281 no.5726 A role for brown adipose tissue in diet-induced thermogenesis Rothwell NJ;Stock MJ
  33. Biochem Pharmacol. v.30 no.12 Na+, K+-ATPase activity and noradrenaline turnover in brown adipose tissue of rats exhibiting diet-induced thermogenesis Rothwell NJ;Stock MJ;Wyllie MG
  34. J Nutr. v.113 no.9 Effects of dietary essential fatty acids on active thermogenin content in rat brown adipose tissue Nedergaard J;Becker W;Cannon B
  35. Biochim Biophys Acta v.1604 no.2 Intrinsic and extrinsic uncoupling of oxidative phosphorylation Kadenbach B.
  36. J Biol Chem. v.274 no.40 The bioenergetics of brown fat mitochondria from UCP1-ablated mice. Ucp1 is not involved in fatty acid-induced de-energization (uncoupling) Matthias A;Jacobsson A;Cannon B;Nedergaard J