Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Pulsatilla Saponin D: the Antitumor Principle from Pulsatilla koreana

  • Published : 2004.09.01
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Abstract

By bioassay-guided separation, an already known saponin, Pulsatilla saponin D was isolated from the root of Pulsatilla koreana Nakai as a antitumor component when evaluated by in vivo antitumor activity as well as in vitro cytotoxic activity test. It showed potent inhibition rate of tumor growth (IR, 82％) at the dose of 6.4 mg/kg on the BDF1 mice bearing LLC cells.

Keywords

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