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The Pharmaceutical Society of Korea (대한약학회)
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Diastereoselective Synthesis of anti-1,2-Aminoalcohol by Palladium(II) Catalyzed Aza-Claisen Rearrangement

  • Published : 2004.02.01
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Abstract

In this study, a highly diastereoselective synthesis of anti-1 ,2-aminoalcohol was explored starting from L-amino acids as chiral sources. The higher yield and diastereoselectivity was shown when the aza-Claisen rearranqement was performed with allylic trichloroacetimidate 6a in the presence of palldium(II) catalyst.

Keywords

References

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