Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Nonspecific Interstitial Pneumonitis Improved After Cyclosporin Therapy

Cyclosporin 치료로 호전된 비특이성 간질성 폐렴 1예

  • Ahn, Sang Mi (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Jo, Suk Kyoung (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Lim, Seung Kwan (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Song, Young Jun (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Choi, Jun Hyuk (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Sheen, Seung Soo (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Oh, Yun Joung (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Choi, Young Hwa (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Park, Kwang Ju (Department of Pulmonary and Critical care, Ajou University School of Medicine) ;
  • Hwang, Sung Chul (Department of Pulmonary and Critical care, Ajou University School of Medicine)
  • 안상미 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 조숙경 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 임승관 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 송영준 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 최준혁 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 신승수 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 오윤정 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 최영화 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 박광주 (아주대학교 의과대학 호흡기 내과학교실) ;
  • 황성철 (아주대학교 의과대학 호흡기 내과학교실)
  • Published : 2003.12.30
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Abstract

Idiopathic interstitial pneumonia is a group of lung disease classified by clinical, radiological and pathologic findings. Steroid is described in many reports as an effective treatment for the idiopathic interstitial pneumonitis. For the treatment of steroid non-responders, immuno-suppressive or cytotoxic agents are used as second line drug of choice. We experienced a case of nonspecific interstitial pneumonitis who was treated initially with glucocorticoid and antibiotics without effects, but later did respond to cyclosporin treatment. This 63 year-old patient was admitted due to dyspnea, cough, and sputum production. He was started on glucocorticoid and antibiotics after he was diagnosed as having nonspecific interstitial pneumonitis by open lung biopsy. The initial steroid treatment was not effective, however, after cyclosprin treatment, the patient showed clinical and radiologic improvements.

비특이성 간질성 폐렴에서 대개의 경우 스테로이드 치료로 호전지만 스테로이드 저항성 인 경우 여러 가지 면역 억제제가 이차 약제로 치료에 시도되고 있으며 본 증례에서는 cyclosprin을 이차약제로 사용해서 좋은 치료 효과를 얻었기에 문헌 고찰과 함께 보고 하는 바이다.

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