Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Two Cases of Microscopic Polyangiitis

현미경적 다발성 혈관염 2예

  • Song, Kyoung Eun (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Im, Seung Guan (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Jo, Sook Kyoung (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Jung, Youn Mu (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Choi, Joon Hyuck (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Sheen, Seung Soo (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Oh, Yoon Jung (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Park, Kwang Joo (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Hwang, Sung Chul (Department of Pulmonary and Critical care Medicine, Ajou University School of Medicine) ;
  • Yim, Hyun Ee (Department of Pathology, Ajou University School of Medicine)
  • 송경은 (아주대학교 의과대학 호흡기내과학교실) ;
  • 임승관 (아주대학교 의과대학 호흡기내과학교실) ;
  • 조숙경 (아주대학교 의과대학 호흡기내과학교실) ;
  • 정연무 (아주대학교 의과대학 호흡기내과학교실) ;
  • 최준혁 (아주대학교 의과대학 호흡기내과학교실) ;
  • 신승수 (아주대학교 의과대학 호흡기내과학교실) ;
  • 오윤정 (아주대학교 의과대학 호흡기내과학교실) ;
  • 박광주 (아주대학교 의과대학 호흡기내과학교실) ;
  • 황성철 (아주대학교 의과대학 호흡기내과학교실) ;
  • 임현이 (아주대학교 의과대학 병리학교실)
  • Published : 2003.12.30
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Abstract

Microscopic polyangiitis is a systemic small-vessel vasculitis that is primarily associated with necrotizing glomerulonephritis and pulmonary capillaritis. Lung involvement is characterized by a diffuse alveolar hemorrhage. However, rarely central nervous system involvement has been reported to be occurred with the microscopic polyangiitis. Relapse of microscopic polyangiitis are reported to be more frequent than those of polyarteritis nodosa, often after a reduction or discontinuation of the therapy. We would like to report two patients with microscopic polyangiitis. One presented with clinical manifestations of both lung and central nervous system involvements and the other was a case of recurrence during steroid tapering following the steroid pulse therapy.

저자들은 급성신부전과 미만성 폐포출혈이 있으면서 중추신경병증이 동반된 현미경적 다발성 혈관염 환자 l예와 특발성 괴사 사구체신염 진단 후 스테로이드 감량 도중 폐침윤이 동반된 전신적인 현미경적 다발성 혈관염의 형태로 재발한 환자 l예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

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