IMMUNE NETWORK
- Volume 3 Issue 2
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- Pages.150-155
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- 2003
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
Effects of Cyclosporin A, FK506, and 3-Deazaadenosine on Acute Graft-versus-host Disease and Survival in Allogeneic Murine Hematopoietic Stem Cell Transplantation
마우스 동종 조혈모세포 이식모델에서 Cyclosporin A, FK506, 3-Deazaadenosine 등의 약제가 급성 이식편대 숙주병과 생존에 미치는 영향
- Jin, Jong Youl (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
- Jeong, Dae Chul (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Eom, Hyeon Seok (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
- Chung, Nak Gyun (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Park, Soo Jeong (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
- Choi, Byung Ock (Department of Therapeutic Radiology, Catholic Hematopoietic Stem Cell Transplantation Center, College of Medicine, The Catholic University of Korea) ;
- Min, Woo Sung (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
- Kim, Hack Ki (Department of Pediatrics, College of Medicine, The Catholic University of Korea) ;
- Kim, Chun Choo (Department of Internal Medicine, College of Medicine, The Catholic University of Korea) ;
- Han, Chi Wha (Department of Internal Medicine, College of Medicine, The Catholic University of Korea)
- 진종률 (가톨릭대학교 의과대학 내과학교실) ;
- 정대철 (가톨릭대학교 의과대학 소아과학교실) ;
- 엄현석 (가톨릭대학교 의과대학 내과학교실) ;
- 정낙균 (가톨릭대학교 의과대학 소아과학교실) ;
- 박수정 (가톨릭대학교 의과대학 내과학교실) ;
- 최병옥 (가톨릭대학교 의과대학 치료방사선과학교실) ;
- 민우성 (가톨릭대학교 의과대학 내과학교실) ;
- 김학기 (가톨릭대학교 의과대학 소아과학교실) ;
- 김춘추 (가톨릭대학교 의과대학 내과학교실) ;
- 한치화 (가톨릭대학교 의과대학 내과학교실)
- Published : 2003.06.30
Abstract
Background: We investigated the effect of donor marrow T cell depletion, administration of FK506, cyclosporin A (CSA), and 3-deazaadenosine (DZA) on graft versus host disease (GVHD) after allogeneic murine hematopoietic stem cell transplantation (HSCT). Methods: We used 4 to 6 week old Balb/c (
Keywords
- 3-Deazaadenosine;
- graft versus host disease;
- allogeneic murine hematopoietic stem cell transplantation