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The Pharmaceutical Society of Korea (대한약학회)
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Design, Synthesis and Anticonvulsive Activities of Potential Prodrugs Linked by Two-carbon Chain

  • Published : 2003.10.01
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Abstract

For the development of new anticonvulsive agents, GABAmimetics such as nipecotic acid, isonipecotic acid, ${\gamma}-aminobutyric$ acid (GABA), ${\gamma}-vinyl$ GABA (vigabatrin) and valproic acid were covalently coupled through an ester bond by a two-carbon linker chain as potential prodrugs and evaluated for their anticonvulsive activities.

Keywords

References

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