Lidocaine Intoxication: Two Fatal Cases

  • Lee, Sang-Ki (National Institute of Scientific Investigation) ;
  • Lee, Soo-Yeun (National Institute of Scientific Investigation) ;
  • In, Sang-Whan (Southern District Office, National Institute of Scientific Investigation) ;
  • Choi, Hwa-Kyung (National Institute of Scientific Investigation) ;
  • Lim, Mi-Ae (National Institute of Scientific Investigation) ;
  • Chung, Kyu-Hyuck (College of Pharmacy, Sungkyunkwan University) ;
  • Chung, Hee-Sun (Southern District Office, National Institute of Scientific Investigation)
  • Published : 2003.04.01

Abstract

We present two fatal cases, a 41-year-old male (case 1) and his 8-year-old daughter (case 2), resulting from acute lidocaine poisoning. Lidocaine was quantified by gas chromatography (GC) analysis using nitrogen-phosphorus detection. The lidocaine concentrations of cases 1 and 2 were: liver, 27.7 $\mu$ g/g and 24.9 $\mu$g/g; spleen, 70.1 $\mu$g/g and 29.9 $\mu$g/g; and gastric contents, 23.6 $\mu$g/g and 42.8 $\mu$g/g, respectively.

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