YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Optimal Synthesis Conditions of Synthetic Aluminum Silicate

합성규산 알루미늄의 최적합성조건

  • Published : 2003.02.01
Download PDF
⟨ Previous Next ⟩

Abstract

Synthetic aluminum silicate was prepared by reacting aluminum sulfate solution with Sodium silicate solution in this study. The optimum synthesis conditions based on the yield of the product were established by applying Box-Wilson experimental design. The results were found to be as follows; Reactant temperature : 50∼72$^{\circ}C$, Concentration of two reactants : 10∼17.6％, Mole ratio of two reactants, [Sod. silicate]/[Al. sulfate) : 4.6∼5.0, Temperature of washing water : 25∼4$0^{\circ}C$, and Drying temperature of product : 50∼$65^{\circ}C$. The physical and chemical properties of synthetic aluminum silicate as medicine were investigated by means of chemical analysis, adsorption test and acid consuming capacity measurements.

Keywords

References

  1. Inorganic Medicinal and Pharmaceutical Chemistry Block;John, H.;Roche;Edward B.;Soine;Taito O.;Wilson;Charles O.
  2. Roger's Inorganic Pharmaceutical Chemistry (6th. ed.) Sorine;Taito O;Wilson;Charles O.
  3. Goodman and Gilman's The Pharmacological Basis of Therapeutics(7th. ed.) Gilman, A. G.;Goodman, L. S.;Rall, T. W.;Murad, F.
  4. 약리학강의 이우주
  5. 대한약전 제 7개정해설서 한국약학대학협의회 약전분과회
  6. Japan 128 Yano;Kiyosi
  7. J. Kor. Pharm. Sic. v.15 Effect of severla manufacturing conditions on a consuming and adsorbing capacity of aluminum silicate Lah, W. L.
  8. Yakhak Hoeji v.33 A Study on the optimum manufacturing conditions of Synthetic aluminum silicate Rhee, G.J.
  9. Yakusaigaku v.22 Studies on powdered preparations X., Acid Neutralizing Velocity of Synthetic Aluminum Silicate and dried Aluminum hydrpxide Gel. Nogami;Hisashi
  10. Japan J. Pharm. and Chem v.22 Tanabe;Hideo;Hasegawa;Eumiko
  11. Bunseki Kagaku v.20 Chiba;Atsushi;Ogawa'Tadahiko https://doi.org/10.2116/bunsekikagaku.20.1002
  12. Yakusaigaku v.25 Relation between Physical properties of Fine Granules of a Few Representative Antacids and the prosess of Manufacture as well as their Acid Neutralizing Capacity Yasui;Chiharu;Kpsasa;Shizuo
  13. Yakusaigaku v.31 Inhibitory Action of Components in Gastric Juic on Antacid Efficacy Studies on Antacids(2) Maekawa;Hideyuki
  14. Yakusaigaku v.22 Studies on Antacids V. Okazaki;Kanzo
  15. J. Roy. Stat. Soc. Ser. B.ⅩⅧ v.1 On the experimental attainments of optimum cinditions Box, G. E. P.;Wilson, K. B.
  16. 의약품기준 및 시험방법 (제 1개정) 국립보건원
  17. 無機醫藥品化學 無機藥品製沽學分科會
  18. 佯藥品, 분류번호
  19. 化學 の 領域 v.15 no.1 最適反應 の 追求 Box-Wilson 計劃とは 岡田壽太郞
  20. 實驗計劃法 岩波書店 增山元三郞
  21. 日本藥局方解說書(第十五改正) 日本藥局方解說島編潗委員會