Asian-Australasian Journal of Animal Sciences

  • 제16권9호
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  • Pages.1291-1296
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  • 2003
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  • 1011-2367(pISSN)
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  • 1976-5517(eISSN)
아세아태평양축산학회 (Asian Australasian Association of Animal Production Societies)
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Effect of Gossypol from Cottonseed Meal Diets on Some Clinico-biochemical Parameters and Humoral Immune Response of Crossbred Calves Fed Barley or Sorghum

  • Pattanaik, A.K. (Centre of Advanced Studies in Animal Nutrition, Indian Veterinary Research Institute) ;
  • Sastry, V.R.B. (Centre of Advanced Studies in Animal Nutrition, Indian Veterinary Research Institute) ;
  • Singh, D.K. (Division of Veterinary Public Health, IVRI) ;
  • Goswami, T.K. (Immunology Section, IVRI) ;
  • Mohanty, D.N. (Division of Animal Reproduction, IVRI)
  • 투고 : 2002.07.24
  • 심사 : 2003.05.12
  • 발행 : 2003.09.01
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초록

Effects of feeding of 9.95 mg free gossypol/kg live weight through cottonseed meal (CSM) were studied in 20 intact male calves fed barley or sorghum as source of cereal during the experimental duration of 210 days. Serum concentration of total protein, albumin, globulin and their ratio did not vary because of protein (gossypol) or cereal sources. Serum level of cholesterol and urea were lower (p<0.05) in sorghum than barley fed calves. Feeding of gossypol through CSM enhanced (p<0.05) serum cholesterol. An interaction between protein and period was observed with respect to serum concentrations of urea, creatinine and alanine transferase. The levels of serum creatinine and alanine transferase increased (p<0.05) following 120 days of experimental feeding in calves fed CSM diets compared to the control animals fed groundnut meal diets. No effect of feeding gossypol was, however, evident on the serum enzymes viz. alanine and aspartate transferases and alkaline phosphatase. Moreover, the source of cereal and protein did not appear to influence the metabolic profile of the calves. Humoral immune response, measured through antibody titre against Brucella abortus S99 innoculation, revealed a delayed and depressed seroreactivity indicative of immunocompromisation because of the phytotoxin gossypol. In conclusion, the feeding of gossypol at the designated levels, although had no deleterious clinico-biochemical manifestations, affected the humoral immune response of the calves.

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피인용 문헌

  1. Gossypol Toxicity from Cottonseed Products vol.2014, pp.1537-744X, 2014, https://doi.org/10.1155/2014/231635
  2. Effects of gossypol from cottonseed cake on the blood profile in sheep vol.48, pp.5, 2016, https://doi.org/10.1007/s11250-016-1039-0
  3. Gossypol as undesirable substance in animal feed - Scientific Opinion of the Panel on Contaminants in the Food Chain : Gossypol as undesirable substance in animal feed - Scientific Opinion of the Pane vol.7, pp.1, 2003, https://doi.org/10.2903/j.efsa.2009.908