Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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[$^1H-NMR$ Assignment of HIV Protease Inhibitor, Procyanidin B3 isolated from Rosa rugosa

  • Park, Jong-Cheol (Department of Oriental Medicine Resources, Sunchon National University) ;
  • Ito, Hideyuki (Faculty of Pharmaceutical Sciences, Okayama University) ;
  • Yoshida, Takashi (Faculty of Pharmaceutical Sciences, Okayama University)
  • Published : 2003.06.01
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Abstract

The underground part of Rosa rugosa Thunb. has been used in Korean folk medicine for treating diabetes. The $^{1}H-NMR$ signal of procyanidin B3 isolated from Rosa rugosa was fully assigned by utilizing $^{1}H-^{1}H$ COSY. Procyandin B3 showed a moderate inhibitory activity against HIV-1 protease.

Keywords

References

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