대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제24권2호
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- Pages.260-268
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- 2003
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- 1226-9174(pISSN)
곽향정기산(藿香正氣散)이 가토(家兎)의 수축혈관에 마치는 영향(影響)
Effects of GwakHyangJungGiSan on the Arterial Contraction in Rabbit
- Sun Jung-Ki (Department of Internal Medicine, Kwang-Dong Oriental Medicine Hospital) ;
- Kim Ho-Hyun (Department of Physiology, College of Oriental Medicine, Semyung University) ;
- Nam Chang-Gyu (Department of Circulatory Internal Medicine, College of Oriental Medicine, Semyung University) ;
- Koo Chang-Mo (Department of Internal Medicine, Kwang-Dong Oriental Medicine Hospital)
- 발행 : 2003.06.01
초록
Object : This study was undertaken to define the mechanism of GwakHyangJungGiSan-induced relaxation in rabbit common carotid artery contracted by agonists. Method : In order to investigate the effect of GwakHyangJungGiSan on rabbit's contracted vascular ring detached from common carotid artery, vascular ring intact or damaged endothelium was used for the experiment using organ bath. To analyze the mechanism of GwakHyangJungGiSan-induced relaxation, GwakHyangJungGiSan extract was infused into contracted vascular ring which had been pretreated by pretreatment of indomethacin(IM), tetraethylammonium chloride(TEA),