Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Prediction of HIV and AIDS Incidence Using a Back-calculation Model in Korea

후향연산 모형 (Back-calculation model)을 이용한 국내 HIV 감염자와 AIDS 환자의 추계

  • Lee, Ju-Young (Division of Epidemiologic Investigation, Department of Infectious Disease Control, National Institute of Health) ;
  • Goh, Un-Yeong (Division of Epidemiologic Investigation, Department of Infectious Disease Control, National Institute of Health) ;
  • Kee, Mee-Kyung (Division of Epidemiologic Investigation, Department of Infectious Disease Control, National Institute of Health) ;
  • Kim, Jee-Yun (Department of Mathematics and Statistics, Inha University) ;
  • Hwang, Jin-Soo (Department of Mathematics and Statistics, Inha University)
  • 이주영 (국립보건원 전염병관리부 역학조사과) ;
  • 고운영 (국립보건원 전염병관리부 역학조사과) ;
  • 기미경 (국립보건원 전염병관리부 역학조사과) ;
  • 김지연 (인하대학교 이과대학 수리통계학부) ;
  • 황진수 (인하대학교 이과대학 수리통계학부)
  • Published : 2002.03.01
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Abstract

Objective : To estimate the status of HIV infection and AIDS incidence using a back-calculation model in Korea. Methods : Back-calculation is a method for estimating the past infection rate using AIDS incidence data. The method has been useful for obtaining short-term projections of AIDS incidence and estimating previous HIV prevalence. If the density of the incubation periods is known, together with the AIDS incidence, we can estimate historical HIV infections and forecast AIDS incidence in any time period up to time t. In this paper, we estimated the number of HIV infections and AIDS incidence according to the distribution of various incubation periods Results : The cumulative numbers of HIV infection from 1991 to 1996 were $708{\sim}1,426$ in Weibull distribution and $918{\sim}1,980$ in Gamma distribution. The projected AIDS incidence in 1997 was $16{\sim}25$ in Weibull distribution and $13{\sim}26$ in Gamma distribution. Conclusions : The estimated cumulative HIV infections from 1991 to 1996 were $1.4{\sim}4.0$ times more than notified cumulative HIV infections. Additionally, the projected AIDS incidence in 1997 was less than the notified AIDS cases. The reason for this underestimation derives from the very low level of HIV prevalence in Korea, further research is required for the distribution of the incubation period of HIV infection in Korea, particularly for the effects of combination treatments.

Keywords

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