The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Effect of Phaseoli Angularis Semen on Biochemical and Histological Changes of Rats Fed High Fat Diet

적소두가 고지방식이로 유발된 비만 흰쥐의 생화학적 및 조직화학적 변화에 미치는 효과

  • Ki-Hyuk, Cho (Department of herbology, College of Oriental Medicine, Kyungsan University) ;
  • Ji-Ha, Park (Department of herbology, College of Oriental Medicine, Kyungsan University) ;
  • Boo-Hyeong, Byun (Department of pathology,College of Oriental Medicine, Kyungsan University) ;
  • Eun-Sook, Lee (Preorientalmedical course, College of Oriental Medicine, Kyungsan University) ;
  • Ho-Young, Choi (Department of herbology, College of Oriental Medicine, Kyunghee University) ;
  • Bu-Il, Seo (Department of herbology, College of Oriental Medicine, Kyungsan University) ;
  • Sung-Hui, Byun (Jae-han Oriental Medical Academy, Kywngsan University)
  • Published : 2002.12.01
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Abstract

목적 : 적소두가 비만에 관하여 어떠한 효능을 발휘하는 가를 살펴보고자 하였다. 방법 : 적소두의 추출물을 고지방식이 흰쥐에 투여한 후 체중, 혈청 중의 변화 및 조직화학적 변화에 미치는 영향을 살펴보았다. 결과 : 체중에 미치는 영향을 살펴보면, 대조군에 비하여 체증이 감소되었으나, 유의성은 없었다. 혈청 중 triglyceride, free fatty acid 함량이 대조군에 비하여 유의성 있게 감소하였다. 부고환 지방세포의 평균 면적에서는 대조군에 비하여 감소 되었으나 유의성은 없었으며 , 간소엽내 지방면적 비율의 감소는 대조군에 비하여 유의성이 있었다. 결론 : 적소두는 임상에서 비만증의 치료에 응용할 수 있을 것으로 생각되며, 특히, 이수소종의 치료법이 필요할 경우에 더 좋은 효능을 발휘할 수 있을 것으로 사료된다.

Keywords

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