Glucanhydrolase from Lipomyces starkeyi KSM 22 as Potential Mouthwash Ingredient

  • Kim, Doman (Faculty of Applied Chemical Engineering, Chonnam National University, East Coastal Marine Bioresources Research Cneter, Kangnung National University) ;
  • Ryu, Su-Jin (Faculty of Applied Chemical Engineering, Chonnam National University) ;
  • Son, Eun-Ju (Department of Periodontology, Chonnam National University) ;
  • Chung, Hyun-Ju (Department of Periodontology, Chonnam National University) ;
  • Kim, Seung-Heuk (Lifenza Co. Ltd.) ;
  • Kim, Do-Won (East Coastal marine Bioresources Research Cneter, Kangnung National University,) ;
  • Day, Donal-F. (Audubon Sugar Institute, Louisiana State University)
  • Published : 2002.12.01

Abstract

A glucanhydrolase (a DXAMase exhibiting both dextranolytic and amylolytic activities) from Lipomyces starkeyi KSM 22 hydrolyzed polysaccharides having ${\alpha}-(1{\rightarrow}3)-,\;{\alpha}(1{\rightarrow}4)-,\;and\;{\alpha}-(1{\rightarrow}6)$-D-glucosidic linkages. The oral hygiene benefits of DXAMase-containing mouthwash were examined in relation to human experimental gingivitis during a 3-week period without brushing. The DXAMase-treated group exhibited a lower increase in plaque accumulation and gingival index score than the chlorhexidine-treated group. The DXAMase-treated group also showed less tongue accumulation, bad taste, and tooth staining, thus indicating a positive role for DXAMase as an antiplaque agent ingredient.

Keywords

References

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