Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Topical Administration of Petrolatum Based Cyclosporine to: .Treatment of Keratoconjunctivitis Sicca in Dogs

Petrolatum을 기질로 한 cyclosporine 국소 점안에 의한 개의 건성 각결막염 치료

  • Published : 2002.06.01
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Abstract

Twenty-nine dogs with chronic keratoconjunctivitis sicca (KCS) were treated by topical administration of a petrolatum based 2% cyclosporine ointment twice daily. Causes and durations of KCS varied. Tear production increased in 25 of 32 eyes and clinical improvement in corneal health was noticed in 35 of 47 eyes. No serious adverse reactions were observed and only mild irritation was noticed by the owners immediately after the application of the ointment in some cases .

Keywords

References

  1. Vet Rec v.119 Keratoconjunctivitis sicca and the treatment of canine colitis Barnett KC
  2. J Am Vet Med Assoc v.200 Keratoconjunctivitis sicca and diabetes mellitus in a dog Barrera R;Mane MC;Rodriguez JF;Jimenez A
  3. J Am Anim Hosp Assoc v.31 A quantitative study of the effects of tribrissen on canine tear production Berger SL;Scagliotti RH;Lund EM https://doi.org/10.5326/15473317-31-3-236
  4. Vet Rec v.117 Possible drug-induced keratoconjunctivitis sicca in a dog Berry AP;Startup FG
  5. Exp Eye Res v.67 Biochemical analysis of ocular surface mucin abnormalities in dry eye: the canine model Hicks SJ;Corfield AP;Kaswan RL;Hirsh S;Stern M;Bara J;Carrington SD https://doi.org/10.1006/exer.1998.0570
  6. Adv Exp Med Biol v.350 Characteristics of a canine model of KCS: effective treatment with topical cyclosporine Kaswan RL
  7. Am J Vet Res v.46 Keratoconjunctivitis sicca: Immunological evaluaton of 62 canine cases Kaswan RL;Martin DL;Dawe DL
  8. Arch Ophthalmol v.107 Spontaneous canine keratoconjunctivitis sicca, A useful model for human keratoconjunctivitis sicca: treatment with cyclosporine eye drops Kaswan RL;Salisbury MA;Ward DA https://doi.org/10.1001/archopht.1989.01070020276038
  9. Vet Clin North Am: Small Anim Pract v.20 A new perspective on canine keratoconjunctivitis sicca. Treatment with ophthalmic cyclosporine Kaswan RL;Salisbury MA https://doi.org/10.1016/S0195-5616(90)50052-2
  10. Vet Rec v.117 Keratoconjunctivitis sicca-an autoimmune condition? Manning PR
  11. J Am Vet Med Assoc v.199 Topical administration of cyclosporine for treatment of keratoconjunctivitis sicca in dogs Morgan RV;Abrams KL
  12. J Am Vet Med Assoc v.199 Clinical evaluation of 1% cyclosporine for topical treatment of keratoconjunctivitis sicca in dogs Olivero DK;Davison MG;English RV;Nasisse MP;Jamieson VE;Gerig TM
  13. Am J Vet Res v.56 Microorganisms isolated from the corneal surface before and during topical cyclosporine treatment in dogs with keratoconjunctivitis sicca Salisbury MAR;Kaswan RL;Brown J
  14. Vet Rec v.137 Treatment of keratoconjunctivitis sicca in dogs with cyclosporine ophthalmic ointment: a European clinical field trial Sansom J;Barnett KC;Neumann W;Schulte-Neumann A;Clerc B;Jegou JP;de Haas V;Weingarten A https://doi.org/10.1136/vr.137.20.504
  15. J Am Vet Med Assoc v.206 Use of pilocarpine for treatment of keratoconjunctivitis sicca Slatter D;Severin GA
  16. J Am Vet Med Assoc v.205 Effect of topical pilocarpine treatment on tear production in dogs Smith EM;Buyukmihci NC;Farver TB
  17. Br J Ophthalmol v.83 New treatment of dry eye: the effect of calcium ointment through eyelid skin delivery Tsubota K;Monden Y;Yagi Y;Goto E;Shimmura S https://doi.org/10.1136/bjo.83.7.767
  18. J Am Vet Med Assoc v.196 Sulfonamiders and keratoconjunctivitis sicca Wilkie DA;Dan Wolf E
  19. Eye v.11 A comparative approach to topical cyclosporine therapy Williams DL https://doi.org/10.1038/eye.1997.126