Analysis of Postpneumonectomy Complication without Balanced Chest Bottle

흉관 삽입술 없이 시행한 전폐절제술 후 발생한 합병증에 대한 분석

  • Kim, Tae-Gyun (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Chung, Won-Sang (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kang, Jung-Ho (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kim, Young-Hak (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Kim, Hyuck (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Jee, Heng-Ok (Department of thoracic and cardiovascular surgery, College of medicine, Hanyang University) ;
  • Lee, Chul-Bum (Department of thoracic and cardiovascular surgery, Kuri Hospital, College of medicine, Hanyang University) ;
  • Ham, Shi-Young (Department of thoracic and cardiovascular surgery, Kuri Hospital, College of medicine, Hanyang University)
  • 김태균 (한양대학교 의과대학 흉부외과학 교실) ;
  • 정원상 (한양대학교 의과대학 흉부외과학 교실) ;
  • 강정호 (한양대학교 의과대학 흉부외과학 교실) ;
  • 김영학 (한양대학교 의과대학 흉부외과학 교실) ;
  • 김혁 (한양대학교 의과대학 흉부외과학 교실) ;
  • 지행옥 (한양대학교 의과대학 흉부외과학 교실) ;
  • 이철범 (한양대학교 의과대학 구리병원 흉부외과학 교실) ;
  • 함시영 (한양대학교 의과대학 구리병원 흉부외과학 교실)
  • Published : 2002.04.01

Abstract

Backgroud: Pneumonectomy carries the possibility of numerous dangerous complications as well as the vast effect the operation itself has on the cardiopulmonary function. Most of operations are done with the insertion of the chest tubes upon completion, but because of the high incidence of pyothorax as its complications, we have tried to analyze and compare the cases without inserting the chest tubes. Material and Method: During a 5 year period from January, 1996 to December 2000, 100 cases, which were operated at the Hanyang University Hospital, were selected using the patient's charts. The age, gender, indication of operation, associated diseases, and operation site(left or right) were classified accordingly and the postoperative complications and mortality were statistically analyzed using the $\chi$ 2-test. After resecting the lung, the intrathoracic pressure was set at -15 ~ -20cm $H_2O$ using the nelaton catheter, and the thoracotomy site was then closed. The gradual collection of the fluid and blood in the thorax of the operated side, as well as the mediastinum location, were observed carefully for 4~5 days postoperatively with the aid of the simple chest x-rays. Result: Of the 100 cases, 16 cases of pulmonary tuberculosis(16%), 81 cases of lung tumor(81%), 2 cases of bronchiectasis(2%), and 1 case of aspergilloma associated bronchiectasis were noted. There were 8 mortality cases(8%), and of the 34 cases(34%), 44 complications were noted. The age, sex, and operation site(left or right) were not statistically significant with the complications. 7 of the 16 cases of pulmonary tuberculosis(44%) and 27 of the 81 cases of lung tumor(33%) had complications, but they were found not to be statistically significant. The increase of the complication rate in the pulmonary tuberculosis patients was 3.86. The evidence of postoperative bleeding was observed in 6 cases with the 3 cases being the pulmonary tuberculosis patients and the 3 cases were others. This shows that the increase in postoperative bleeding in the pulmonary tuberculosis is statistically significant(p=0.019). Of the 100 cases, there were 8 mortality cases(8%), with 5 cases from the 81 cases of the lung tumor group(6.1%), 3 cases from the 16 cases of pulmonary tuberculoses group(18.7%).

배경: 전폐절제술은 수술 그 자체가 환자의 심폐기능에 큰 영향을 줄 수 있으며 또한 합병증이 치명적 결과를 초래하는 경우가 많아, 합병증과 그 연관 인자 간의 많은 연구가 있어 왔다. 수술적 수기로 대부분 흉관을 삽입 후 수술을 종료하는 방법을 많이 사용하고 있으나 합병증 중 농흉의 높은 비율로 인해 그 위험 인자 중 융관 삽입술 없이 전폐절제술을 시행하여 발생한 술후 합병증에 대해 비교 분석하여 보고하고자 한다. 대상 및 방법: 1996년 1월부터 2000년 12월 까지 약 5년간 한양대학병원 흉부외과에서 수술 치험한 100례를 대상으로 환자기록지를 참조하여 나이와 성, 수술적응, 관련질환, 수술 환측으로 분류하고 술후 발생한 합병증과 사망률 등을 $\chi$$^2$-test 사용하여 통계학적으로 처리하였다. 수술은 전폐절제술 후 흉막강 내 압력을 유치도뇨관(nelaton catheter)을 사용하여 -15~-20 cm$H_2O$로 한 후 개흉창을 닫고 4~5일 이상 단순 흥부 촬영으로 액체 저류 및 출혈, 종격동의 위치를 감시 하였다. 결과: 총 100례 중 폐결핵 16례(16%), 폐종양 81례(81%), 기관지 확장증 2례(2%), 폐국균종을 동반한 기관지 확장증 1례(1%)였다. 수술 후 사망은 총 100례 중 8례로 8%열으며 합병증은 34명(34%)에서 44례로 조사되었다. 합병증은 나이, 성별, 수술 측과는 통계적 상관 관계가 없었으며, 결핵환자 16명 중 7명(44%), 폐종양 81명 중 27명(33%)로 결핵 환자에서 폐종양에 비해 3.86배로 합병률이 높았으나 통계적인 유의성은 확인할 수 없었다. 또한 술후 발생한 출혈 6례에서 결핵 16례 중 3례, 폐종양 및 기타 84례 중 3례로 결핵에서 술후 출혈률이 통계적으로 의미있게 높았다(p=0.019) 사망률은 총 100례 중 8례(8%)로 폐종양 81례 중 5례(6.1%), 폐결핵 16례 중 3례(18.7%)로 결핵 환자에서 폐종양에 비해 3.93배로 사망률이 높았으나 통계학적으로 유의성은 확인 할 수 없었다.

Keywords

References

  1. J Thorac Cardiovasc Surg v.57 The postpneumonectomy space : Factors influencing its obliteration. Suarez J;Clagett OT;Brown AL.
  2. JJAT v.22 Result of pneumonectomy for pulmonary tuberculosis. Kanou Houzi
  3. 대흉외지 v.26 전폐절제술후 발생한 합병증에 대한 분석 허강배;조성래;김수현 등
  4. 대흉외지 v.28 전폐절제술에 관한 임상적 연구. 권은수;정황규
  5. 대흉외지 v.3 일측폐 전적출술 100례에 대한 임상적 고찰 김진식;김의윤;손재현
  6. J Thorac Cardiovasc Surg v.86 Modern thirty-day operation mortality for surgical resection in lung cancer Ginsberg RJ;Hill LD;Eagan RT(et al)
  7. Ann Thorac Surg v.72 Empyema and bronchopleural fistula after pneumonectomy: factors affecting incidence. Deschamps C;Bernard A;Nicholas III FC(et al) https://doi.org/10.1016/S0003-4975(01)02681-9
  8. Ann Thorac Surg v.62 pneumonectomy for chronic infection is a high risk prcedure. Gilbert Massard;Ahmad Dabbagh https://doi.org/10.1016/0003-4975(96)00596-6
  9. 대흉외지 v.22 폐결핵의 외과적 요법에 대한 임상적 고찰 고재웅;임진수;최형호;장정수;장동철;김승철
  10. J Thorac Cardiovasc Surg v.45 Aprocedure for the management of postpnumonectomy empyema. Clagett OT;Geraci JE
  11. Ann Thorac Surg v.52 Bronchopleural fistula after sstapled closure of bronchus. Vester SR;Faber LP;Kittle CF(et al) https://doi.org/10.1016/0003-4975(91)90009-F
  12. J Thorc Cardiovasc Surg v.105 Indications, risk, and results of completion pneumonectomy. Gregoire J;Deslauries J;Guojin L;Rouleau J.
  13. Kyobu Geka v.48 Brobchopleural fistula following the use of automatic stapling device for lung cancer. Motohiro A;Hirota N;Komatsu H(et al)
  14. Ann Thorac Surg v.62 Pneumonectomy for chronic infection is a high risk procedure. Massard G;Dabbagh A;Wihlm JM(et al) https://doi.org/10.1016/0003-4975(96)00596-6
  15. J Surg Oncol v.61 Postoperative complications after pneumonectomy for treatment of lung cancer:multivariate analysis. Mitsudomi T;Mizoue T;Yoshimatsu T(et al) https://doi.org/10.1002/(SICI)1096-9098(199603)61:3<218::AID-JSO11>3.0.CO;2-3
  16. Nippon Kyobu Geka Gakkai Zasshi v.44 Analysis of risk factors for development of bronchopleural fistula after pneumonectomy for lung cancer. Haraguchi S;Koizumi K;Gomibuchi M(et al)
  17. Eur J Cardiothorac Surg v.16 Closure of the bronchial stump by manual suture and incidence of bronchopleural fistula in a series of 209 pneumonectomies for lung cancer. Hubaut JJ;Baron O;Al Habash O(et al) https://doi.org/10.1016/S1010-7940(99)00290-0
  18. Scand Cardivasc J v.33 Incidence, risk factors, and management of bronchopleural fistulae after pneumonectomy. De Perrot M;Licker M;Robert J(et al) https://doi.org/10.1080/14017439950141812