The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effect of the Extract of Angelica gigas on the Serum Alcohol and Acetaldehyde Concentration in Rats

당귀추출물 전처치가 Rat의 혈중 알코올 및 알데히드 농도에 미치는 영향

  • Song, Jae-Chul (Institutional Research Board, Pochon CHA University) ;
  • Park, Jung-Mi (Institutional Research Board, Pochon CHA University) ;
  • Kim, Sang-Woo (Institutional Research Board, Pochon CHA University) ;
  • Lee, Hee-Sul (Institutional Research Board, Pochon CHA University) ;
  • Jung, Woo-Sang (Institutional Research Board, Pochon CHA University)
  • 송재철 (포천중문의대 분당차병원 임상의학위원회) ;
  • 박정미 (포천중문의대 분당차병원 임상의학위원회) ;
  • 김상우 (포천중문의대 분당차병원 임상의학위원회) ;
  • ;
  • 정우상 (포천중문의대 분당차병원 임상의학위원회)
  • Published : 2002.06.30
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Abstract

Objectives : Our study was designed to assess whether the extract of Angelica gigas can lower serum alcohol and acetaldehyde concentration in drunken rats. Methods : We divided Sprague-Dawley male rats into 3 groups of a Vehicle control, Positive control and Angelica gigas group. Serum alcohol and acetaldehyde levels were checked at baseline, 0.5, 1, 2 and 4 hours after drinking ethanol. Independent t-test was performed to assess the difference of the serum concentrations between the Angelica gigas induced group and the control group. Results : Angelica gigas lowered the serum acetaldehyde concentration. However, it did not lower alcohol concentration effect. Conclusions : We assume that Angelica gigas could be effective for alcohol induced hangover.

Keywords

References

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