IMMUNE NETWORK
- Volume 1 Issue 3
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- Pages.213-220
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- 2001
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- 1598-2629(pISSN)
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- 2092-6685(eISSN)
Protective effect of euonymus alatus extract on experimental liver injury in mice
Euonymus alatus 추출물의 실험적 간 손상 억제
- Shin, Sook-Jeong (Department of Microbiology, Chonbuk National University Medical School) ;
- Lee, Byung-Yong (Department of Microbiology, Chonbuk National University Medical School) ;
- Shin, Dong-Keun (Department of Microbiology, Chonbuk National University Medical School) ;
- Lee, Jeong-Ho (Department of Microbiology, Chonbuk National University Medical School)
- 신숙정 (전북대학교 의과대학 미생물학교실) ;
- 이병용 (전북대학교 의과대학 미생물학교실) ;
- 신동근 (전북대학교 의과대학 미생물학교실) ;
- 이정호 (전북대학교 의과대학 미생물학교실)
- Published : 2001.12.31
Abstract
Background: A previous study has shown that Euonymus alatus (EA) has an antidotic activities against inflammation, suggesting possibility that EA can exert this beneficial effects to liver injury by an initial protection against drug-induced hepatocyte demage. The present study was undertaken to evaluate the protective effect of EA-extract on experimentally induced hepatitis in ICR mice and to investigate some mechanisms responsible for its action. Methods: Water EA extract was used in this experiments. The mice received i.p. a dose of 700 mg/kg galactosamine (GalN) together with