Pediatric Infection and Vaccine

The Korean Society of Pediatric Infectious Diseases (대한소아감염학회)
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Two Case of Burkholderia cepacia Sepsis

Burkholderia cepacia 패혈증 2례

  • Park, Seong Shik (Department of Pediatrics, College of Medicine, Pusan National University) ;
  • Ahn, Sung Ryon (Department of Pediatrics, College of Medicine, Pusan National University) ;
  • Park, Su Eun (Department of Pediatrics, College of Medicine, Pusan National University) ;
  • Lim, Young Tak (Department of Pediatrics, College of Medicine, Pusan National University) ;
  • Chang, Chul Hun (Department of Clinical Pathology, College of Medicine, Pusan National University)
  • 박성식 (부산대학교 의과대학 소아과학교실) ;
  • 안성연 (부산대학교 의과대학 소아과학교실) ;
  • 박수은 (부산대학교 의과대학 소아과학교실) ;
  • 임영탁 (부산대학교 의과대학 소아과학교실) ;
  • 장철훈 (부산대학교 의과대학 임상병리학교실)
  • Published : 2001.11.30
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Abstract

Burkholderia cepacia, a widespread gram-negative environmental bacillus associated with nosocomial infection, is considered to be of relatively low virulence and rarely to cause invasive disease in immunocompromised patients. Nosocomial infections resulting from the use of contaminted medication, antiseptics and instruments have also been reported in otherwise healthy hosts. We experienced two cases of B. cepacia sepsis in 10 year-old male who was medicated with the anticancer drugs for the treatment of acute lymphoblastic leukemia(ALL) and in 15 day-old newborn who was examined with voiding vesicourethrography(VCUG) for the evaluation of congenital hydronephrosis. The organism isolated from serial blood culture in ALL patient and from serial blood culture and urine culture in newborn examined with VCUG. The former ALL patient improved after antibacterial medication of imipenem and the latter newborn improved after treatment with imipenem and trimethoprim-sulfamethoxazole.

저자들은 급성 림프구성 백혈병으로 진단받고 항암 약물 치료 중인 10세 남아와 선천성 수신증으로 진단받고 도뇨관 유치 후 배뇨성 방광 요도 조영술을 촬영한 신생아에서 발생된 Burkholderia cepacia 패혈증을 혈액 배양 검사로 진단하고 이에 감수성이 있는 항생제 투여 후 임상적으로 호전을 보였기에 문헌고찰과 함께 보고하는 바이다.

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