대한핵의학회지 (The Korean Journal of Nuclear Medicine)
- 제35권6호
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- Pages.343-351
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- 2001
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- 1225-6714(pISSN)
PET과 SPECT에서 나타나는 뇌허혈후 과관류
Cerebral Postischemic Hyperperfusion in PET and SPECT
- 조인호 (영남대학교 부속병원 핵의학과)
- Cho, Ihn-Ho (Department of nuclear medicine, Yeungnam university hospital)
- 발행 : 2001.12.31
초록
Cerebral post-ischemic hyperperfusion has been observed at the acute and subacute periods of ischemic stroke. In the animal stroke model, early post-ischemic hyperperfusion is the mark of recanalization of the occluded artery with reperfusion. In the PET studios of both humans and experimental animals, early post-ischemic hyperperfusion is not a key factor in the development of tissue infarction and indicates the spontaneous reperfusion of the ischemic brain tissue without late infarction or with small infarction. But late post-ischemic hyperperfusion shows the worse prognosis with reperfusion injury associated with brain tissue necrosis. Early post-ischemic hyperperfusion defined by PET and SPECT may be useful in predicting the prognosis of ischemic stroke and the effect of thrombolytic therapy.