Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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Safety Evaluation of Genetically Modified Organisms (GMO) for a 90-day Exposure in Rats

랫드에서 유전자 재조합 식품(GMO)의 90일간 노출에 대한 안전성 평가

  • 김태융 (서울대학교 수의과대학 공중보건학교실, 농림부 축산국 가축위생과) ;
  • 제정환 (서울대학교 수의과대학 공중보건학교실) ;
  • 조성대 (서울대학교 수의과대학 공중보건학교실) ;
  • 강경선 (서울대학교 수의과대학 공중보건학교실) ;
  • 이영순 (서울대학교 수의과대학 공중보건학교실)
  • Published : 2001.03.01
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Abstract

We performed to evaluate the safety of GMOs for a long term exposure in Sprague-Dawley (SD) rats. In this study, groups often or fifteen SD rats were fed one of the following four diets for 90 days: (1) AIN-76A rodent diet only; (2) AIN-76A rodent diet containing 5% genetically modified soybean from USA; (3) AIN-76A rodent diet containing 5% genetically non-modified soybean from USA; (4) AIN-76A rodent diet containing 5% genetically non-modified soybean from Korea. The effects of AIN-76A rodent diet containing genetically modified soybean on body weights, food uptake, water consumption, hematology, serum bio-chemistry, urinalysis, organ weights, gross findings and histopathological findings were not significantly different, compared with others. Taken together, these results suggested that genetically modified soybean did not induce any toxic effects in rats treated for 90 days.

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