Isolation of Antimicrobical Compounds from the Ethyl Acetate Extract of Sophora flavescens

고삼의 에틸 아세테이트 추출물로부터 항균물질의 분리

  • 이현옥 (원광보건대학 치위생과) ;
  • 박낭규 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 정승일 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 김윤철 (약학과) ;
  • 백승화 (한국한약학 연구원)
  • Published : 2001.12.01

Abstract

Two flavanones, (2S) -2'-methoxykurarinones (1) and kurarinones (2) , were isolated from the ethyl acetate extract of the roots of Sophora flavescense Ait. Their structrures were elucidated using NMR, UV and IR spectral analysis. These compounds exhibited a moderate antimicrobial activities against Staphylococcus aureus, Staphylococcus epidermidis Pseudomonas Putida and a weak anti-fungal activity against Candida albicans.

Keywords

References

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