Characterization of a Coagulase-Negative Staphylococcus sp. Isolated from Raw-Milk having Reduced Susceptibility to Vancomycin

원유시료에서 분리된 반코마이신 저항성 Coagulase-Negative Staphylococcus 균주의 특성

  • Published : 2001.10.01

Abstract

Coagulase-negative Staphylococcus sp #39, isolated from raw-milk showed reduced susceptibility to vancomycin. The minimun inhibitory concentration for strain #39 was at 8$\mu\textrm{g}$ of vancomycin per ml. Transmitting electron microscopy displayed that this strain had a 2.5-3.5 times thicker cell wall than a vancomucin sensitive strain of Staphylococcus sp. The strain #39 also had an increased cell volume. These data indicate that the reduced susceptibility may be due to the thickness of the cell wall of the test strain.

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References

  1. Am.J.Med. v.91 Methicillin-resistant Staphylococus aureus;implication for the 1990s and effective control measures Wenzel,R.P.;Nettleman,R.N.;Pfaller,M.A.
  2. The staphylococci in human disease Resistance to antimicrobial agents other than β-lactamase Paulsen,I.T.;Firth,N.;Skurray,R.A.;K.B.Crossley(ed.);G.L.Archer(ed.)
  3. Morbid.Mortal.Weekly Rep. v.46 no.624 Centers for Disease Control:Staphylococcus aureus with reduced susceptibility to vancomycin
  4. N.Eng.J.Med. v.317 no.766 Vancomycin-resistant staphylococcus Schwalbe,R.S.;Stapleton,J.T.;Gilligan,P.H.
  5. Morbid.Mortal.Weeky Rep. v.46 no.813 Centers for Disease Control:Staphylococcus aureus with reduced susceptibility to vancomycin-United States
  6. National Committee for Clinical Laboratory Standards National Committee for Clinical Laboratory Standards Methods for dilution antimicrobial susceptibility tests for bacteia that grow aerobically,Approved standard M7-A2
  7. Drug Res.Updates v.1 no.135 Vancomycin resistance in staphylococci Hiramatsu,K.
  8. FEMS Microbiol.Lett. v.93 no.195 Co-transger of vancomycin and other resistance genes from Enterococcus faecalis NCTC 12201 to Staphylococcus aureus Noble,W.C.;Virani,Z.;Cree,R.G.A.
  9. Infect.Immun. v.62 no.1406 Autolysis-defective mutant of Staphylococcus aureus:pathogenical considerations,genetic mapping and electron microscopic studies Manin,N.;Baddour,L.M.;Offutt,D.Q.;Vijaranakul,U.;Nadakavukaren,M.J.;Jayaswal,R.K.
  10. Lancet v.35 no.57 Vancomycin-resistant enterococci. Uttley,A.H.C.;Collins,C.H.;Naidoo,J.;George,R.C.
  11. J.Antimicrob.Chemether. v.34 no.507 Farm animal as putative reservoir for vancomycin-resistant enterococci infection in man Bates,J.;Jordens,J.Z.;Griffith,D.T.