Journal of Microbiology and Biotechnology

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Antibacterial Compound against Pasturella multiocida and Actinobacillus pleuropneumoniae Causing Porcine Pneumonia

  • Lyoo, Young-Soo (Department of Veterinary Medicine, Konkuk University) ;
  • Park, Dong-Ki (Department of Applied Biology & Chemistry, Konkuk University) ;
  • Lee, Sang-Mok (Department of Veterinary Medicine, Konkuk University) ;
  • Choi, Yi-Don (Department of Veterinary Medicine, Konkuk University) ;
  • Jung, Ji-Hyun (Department of Applied Biology & Chemistry, Konkuk University) ;
  • Jun, Tae-Il (Department of Applied Biology & Chemistry, Konkuk University) ;
  • Ahn, Hong-Suk (Department of Applied Biology & Chemistry, Konkuk University) ;
  • Lee, Chul-Hoon (Department of Medical Genetics & Institute of Biomedical Science, College of Medicine, Hanyang University) ;
  • Lim, Yoong-Ho (Department of Applied Biology & Chemistry, Konkuk University)
  • Published : 2001.04.01
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Abstract

Porcine pneumonia is caused by Pasturella multiocida and Actinobacillus pleuropneumoniae. To identify a potent drug for antipneumonia therapy, several herbal compounds showing antibacterial effects were screened, and it was found that a methanol extract of Coptidis rhizoma root stem exhibited activity against both pneumonia-causing bacteria. Using an activity-guided fragmentation procedure, an isoquinoline alkaloid was isolated which would be responsible for the antibacterial activities against P. multocida and A. pleuropneumoniae.

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References

  1. J. Magn. Reson. v.43 A simple method for suppressing dispersion-mode contributions in nmr spectra: the 'pseudo echo' Bax, A.;R. Freeman
  2. J. Magn. Reson. v.55 Correlation of proton and nitrogen-15 chemical shifts by multiple quantum nmr Bax, A.;R. Griffey;B. Hawkins
  3. J. Am. Chem. Soc. v.108 ¹H and 13C assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum nmr Bax, A.;M. Summers
  4. J. Magn. Reson. v.48 Distortionless enhancement of nmr signals by polarization transfer Dodrell, D.;D. Pegg;M. Bendall
  5. J. Endod. v.1 antibiotic sensitivities of enterococci isolated from treated root canals Heintz, C.;R. Deblinger;S. Oliet
  6. J. Chromatogr. v.679 Determination of trace impurities of peptides and alkaloids by capillary electrophoresision spray mass spectrometry Hsieh, F.;J. Cai;J. Henion
  7. Planta Med. v.64 Structure-activity relationships of photoberberines having antimicrobial activity Iwasa, K.;H. Nanba;D. Lee;S. Kang
  8. J. Microbiol. Biotechnol. v.10 Comparison of the solution structure of vancomycin with its x-ray crystallographic structure Lee, C.-H.;H. Kyung;Y. Lim
  9. J. Microbiol. Biotechnol. v.9 Antibacterial activity of antimycotic miconazole against methicillin-resistant Staphylococcus aureus Lee, S.;C. Kim
  10. J. Microbiol. Biotechnol. v.9 Isolation of sphinin, an inhibitor of sphingomyelinase, from Streptomyces sp. F50970 Lim, S.;W. Park
  11. J. Microbiol. Biotechnol. v.9 10-Hydroxyocatadecanoic acid produced by Lactococcus lactis subsp. lactis as a part of flocculent aggregate Park, H.;Y. Lim;Y. Kim;K. Kyung
  12. Agric. Chem. Biotechnol. v.43 Determination of the substituted position of piperazine in substitution reaction of oxazolidinones Park, J.;J. Suh;J. Kim;C. Kim;K. Kim;Y. Lim
  13. J. Microbiol. Biotechnol. v.10 Screening and identification of an antifungal Pseudomonas sp. that suppresses balloon flower root rot caused by Rhyzoctonia solani Ryu, J.;S. Lee;S. Lee;D. Kim;S. Cho;S. Park;D. Bae;K. Park;H. Yun
  14. Am. J. Vet. Res. v.55 In vitro susceptibility of equine salmonella strains to trimethoprim and sulfonamide alone or in combination van Duijkern, E.;B. van Klingeren;A. Vulto;M. van Oldritenbourg;H. Breukink;A. van Miert