KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Development of Hollow-fiber Reactor System for the Production of Chiral 1,2-epoxy-7-octene by Microbial Enantioselective Hydrolysis Reaction

미생물 입체선택성 가수분해반응을 이용한 광학활성 1,2-epoxy-7-octene 생산을 위한 Hollow-fiber 반응기 시스템 개발

  • 이은열 (경성대학교 공과대학 식품공학과) ;
  • 김희숙 (경성대학교 공과대학 식품공학과)
  • Published : 2001.06.01
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Abstract

The development of hollow fiber reactor system for the production of chiral 1,2-epoxy-7-octence by epoxide hydrolase for Rhodotorula glutinis was investigated. Dodecane with high solubility of the racemic substrate passed through the lumen side of the hollow fiber reactor and cell suspension was recirculated through the shell side. The 2nd hollow fiber reactor was coupled to the production reactor to extract the diol byproduct which was the inhibitor of epoxide hydrolase. Optically pure (S)-1,2-epoxy-7-octene (0.6 M in dodecane) could be obtained using hollow-fiber reactor system.

Keywords

References

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