KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Glucose Binging Affinity of DPPC-ODA-asparagine and Stability of Liposomes Adding Cholesterol

DPPC-ODA-asparagine 리포솜의 포도당 친화도 및 콜레스테롤 첨가에 따른 안정성 측정

  • Published : 2001.04.01
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Abstract

Liposome-amino acid conjugates were prepared using dipalmitolyphosphatidylcholine(DPPC) and hydrophobically modified asparagine. A microdialyzer was used to measure glucose diffusion. The glucose binding affinity of DPPC-ODA-asparagine liposomes higher than that of DPPC liposomes and distilled water. The size of DPPC-ODA-asparagine was approximately 75-150 nm. Cholesterol increased the stability of liposomes, and reduced the size of liposome particles.

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