The Journal of Korean Society for Radiation Therapy (대한방사선치료학회지)
- Volume 13 Issue 1
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- Pages.14-22
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- 2001
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- 1598-8449(pISSN)
Volumetrical changes of liver associated with breathing and its impact to normal tissue complication probability
호흡에 따른 간장용적의 변화와 정상조직손상확율에 미치는 영향에 관한 연구
- Cho Jung Hee (Dept. of Radiation Oncology, Yonsei University, College of Medicine) ;
- Kim Joo Ho (Dept. of Radiation Oncology, Yonsei University, College of Medicine) ;
- Lee Suk (Dept. of Radiation Oncology, Yonsei University, College of Medicine) ;
- Park Je Il (Dept. of Radiation Oncology, Yonsei University, College of Medicine)
- Published : 2001.12.01
Abstract
Purpose: The aim of this study is to investigate geometrical and volumetrical changes of liver due to breathing and its impact to NTCP. In order to attain better treatment results it should be considered deliberately during planning session. Mehtods and Materials : Seven patients were examined in this study who have done TACE for accurate tumor margin drawing. After contrast media injection, C-T scan data were obtained in supine position during breathing free, inhalation and exhalation, respectively. For all patients C-T scan were done with same scanning parameters- 5 mm index, 5 mm thickness and pitch 1. Based on C-T data we have measured differences of each variables between breathing status such as changes of total and remained liver volumes, GTV, beam path length and superior to inferior shift. NTCP were calculated using Lyman's effective volume DVH reduction scheme and for this NTCP calculation, the V50 was computed from DVH and each m, n value were referred from Burmans data. Results : The measured total tilter volume and the remained liver volume changed between inspiration and expiration about