Korean Journal of Pharmacognosy (생약학회지)
- Volume 32 Issue 2 Serial No. 125
- /
- Pages.116-120
- /
- 2001
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- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Quantitative Determination of 5-Hydroxymethyl-2-furaldehyde in the Rehmanniae Radix Preparata Samples at Various Processing Stages
수치에 따른 숙지황 중의 5-hydroxymethyl-2-furaldehyde 함량분석
-
Hwang, Suk-Yeon
(College of Pharmacy, Chungbuk National University)
;
-
Hwang, Bang-Yeon
(College of Pharmacy, Chungbuk National University)
;
- Choi, Woo-Hoi (College of Pharmacy, Chungbuk National University) ;
- Jung, Han-Jin (Sewon Pharmaceutical Co., Ltd.) ;
- Huh, Jae-Doo (Crown Pharmaceutical Co., Ltd.) ;
-
Lee, Kyong-Soon
(College of Pharmacy, Chungbuk National University)
;
-
Ro, Jai-Seup
(College of Pharmacy, Chungbuk National University)
-
황석연
(충북대학교 약학대학)
;
-
황방연
(충북대학교 약학대학)
;
- 최우희 (충북대학교 약학대학) ;
- 정한진 (세원제약(주)) ;
- 허재두 (크라운제약(주)) ;
-
이경순
(충북대학교 약학대학)
;
-
노재섭
(충북대학교 약학대학)
- Published : 2001.06.30
Abstract
In order to determine the content of 5-hydroxymethyl-2-furaldehyde (5-HMF) in the Rehmanniae Radix Preparata, 5-HMF was isolated from the EtOAc fraction of the Rehmanniae Radix Preparata samples and identified by spectroscopic and physicochemical evidences. Twenty one samples prepared on the basis of increasing number of stewing times with wine were analyzed by HPLC. From this analysis, it was revealed that the samples processed under one to nine times of stewing showed increasing pattern in 5-HMF contents. And the samples processed under 9 to 18 times of stewing showed 0.53-0.74% in 5-HMF contents. However, for those samples processed more than 19 times, 5-HMF content profile showed decreasing pattern.
Keywords
- Rehmanniae Radix Preparata;
- 5-hydroxymethyl-2-furaldehyde;
- quantitative determination;
- stewing with wine