대한수의학회지 (Korean Journal of Veterinary Research)
- 제40권4호
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- Pages.691-699
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- 2000
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- 2466-1384(pISSN)
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- 2466-1392(eISSN)
기니피그 유문부 윤상근의 서파 몇 자발적 수축에 대한 nitric oxide donor의 억제적 작용
The inhibitory action of nitric oxide donor on the slow wave and spontaneous contraction in the guinea pig antral circular muscle
- Kim, Tea-wan (Department of Physiology, College of Veterinary Medicine, Seoul National University) ;
- La, Jun-ho (Department of Physiology, College of Veterinary Medicine, Seoul National University) ;
- Yang, Il-suk (Department of Physiology, College of Veterinary Medicine, Seoul National University)
- 심사 : 2000.11.23
- 발행 : 2000.12.20
초록
We investigated the effects of nitric oxide (NO) donors, S-nitroso-L-cysteine (Cys-NO) and 3-morpholinosydnonimine hydrochloride (SIN-1), on the contractile and electrical activity of the circular muscle of guinea pig gastric antrum by using intracellular microelectrode technique. The gastric antral circular muscle showed spontaneous phasic contraction and slow wave of membrane potential. Cys-NO (