The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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An Experimental Study on the Antithrombotic Effects of CARTHAMUS TINCTORIUS

홍화의 항혈전작용에 대한 실험적 연구

  • 안종석 (대전대학교 한의과대학 심계내과학교실) ;
  • 황치원 (대전대학교 한의과대학 심계내과학교실)
  • Published : 2000.12.01
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Abstract

Objectives: The purpose of this study was to investigate the antithrombotic effect of Carthamus tinctorius. Methods: SD rats were used to investigate the inhibitive effect of platelet aggregation (in vitro & in vivo), prothrombin time, platelet count. Mice were used to investigate the survival rate after injection of collagen & epinepbrine. Results: 1. The inhibitive effect of platelet aggregation (in vitro & in vivo) were increased significantly in all groups. 2. Prothrombin time was decreased in both groups. 3. Platelet count was decreased significantly in sample A. 4. Survival rate after injection of collagen & epinepbrine was increased in sample B. Conclusion: According to the above results, it is suggested that Carthamus tinctorius has antithrombotic effects.

Keywords

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