The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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An Experimental Study on Brain Damage and Cardiovascular System Effects of Angelicae Gigantis Radix Extract

당귀가 백서의 뇌손상 및 심혈관계에 미치는 영향

  • 김용진 (대전대학교 한의과대학 심계내과학교실) ;
  • 황치원 (대전대학교 한의과대학 심계내과학교실)
  • Published : 2000.12.01
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Abstract

Objective : The purpose of this study was to investigate the effects of Angelicae Gigantis Radix on brain damage and the cardiovascular system. Method : By administration Angelicae Gigantis Radix, we compared treated groups with not treated groups, in view of five points as follows $\circled1$ the intervascular eNOS, $\circled2$ the blood pressure of SHR, $\circled3$ the transcription of the Kir6.2, $\circled4$ the survival time of the rats when common carotid artery was ligated, and $\circled5$ antiplatelet aggregation. Result : In this experiment, Angelicae Gigantis Radix treated group showed significant produced in the intervascular eNOS and decreased the blood pressure of SHR, increased the transcription of the Kir6.2 and SUR significantly in all Treated groups, prolonged the survival time of the rats when common carotid artery, showed the effects on antiplatelet aggregation. Conclusion : According to the above results, Angelicae Gigantis Radix can protect the brain damage and have cardiovascular system effect.

Keywords

References

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