Abstract
Objectives : In oriental medicine, Daeseungki-tang is one of the most useful prescriptions for the therapy of constipation. And we also frequently use this prescription for constipated stroke patients. Methods : In order to identify the effects of Daeseungki-tang on constipated stroke patients, we administrated the extract of Daeseungki-tang(code number, HH264) to constipated stroke patients. We gave the medicine in two ways, one-pack group and two-pack group by random allocation and investigated the amount of stool, the frequency of defecation, the stool-form and the changes of blood pressure and body temperature before and after defecation. We also tried to examine the difference of symptoms between defecation-group and non-defecation group. Results : 1. There were no distinct symptoms between defecation-group and non-defecation-group in one-pack group. 2. After defecation, body temperature decreased significantly(P<0.05) in one-pack group and blood pressure decreased significantly(P<0.05) in two-pack group. 3. As for the stool-form, watery-soft was 41.9% in the firstt defecation and 47.1 % in the second defecation. 4. In one-pack group(23 cases), 13 cases(57%) defecated and 10 cases(43%) didn't defecate. And in two-pack group(24 cases), 19 cases(80%) defecated and 5 cases(20%) didn't defecate. These results meant that the effect of Daeseungki-tang was dose dependent. The amount of stool and the frequency of defecation were also dose dependent.
