The Anti-Inflammatory Effects of Takrisodok-eum in the Ong-Juh(옹저)

옹저에 사용되는 탁리소독음의 항염증효과

  • Ho-Gun, Kang (Department of Molecular Biology, College of Natural Sciences, Pusan National University) ;
  • Byung-Tae, Choi (Department of Molecular Biology, College of Natural Sciences, Pusan National University) ;
  • Young-Hee, Kim (Department of Oriental Medicine, College of Oriental Medicine, Dongeui University) ;
  • Ho-Sung, Kang (Department of Oriental Medicine, College of Oriental Medicine, Dongeui University) ;
  • Han-Do, Kim (Department of Oriental Medicine, College of Oriental Medicine, Dongeui University) ;
  • Woo-Shin, Ko (Department of Molecular Biology, College of Natural Sciences, Pusan National University)
  • Published : 2000.03.01

Abstract

탁리소독음이 옹저에 있어 항염증 효과를 살펴보고자 NO의 농도, 세포 생존도, iNOS의 표현 및 $TNF-{\alpha}$의 농도를 실험한 결과, NO의 농도는 현저하게 감소하였고 세포 생존도는 탁리소독음에 의하여 영향을 받지 않았으며 iNOS의 표현에 있어서 iNOS의 고도가 현저하게 낮아졌고 $TNF-{\alpha}$의 농도는 현저한 변화가 없었다. 이상을 살펴볼 때 탁리소독음이 옹저에 있어 항염증효과가 있음을 알 수 있었다. 또한 탁리소독음이 충분히 대식세포의 역할을 대신하며 이 이외의 신호경로가 염증기전에 작용한 것으로 생각되며 많은 연구가 요할 것으로 사료된다.

Keywords

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