한국한의학연구원논문집 (Korean Journal of Oriental Medicine)
- 제6권1호
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- Pages.107-116
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- 2000
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- 1229-3377(pISSN)
Vibrio parahemolyticus에 대한 한방처방(금궤요략) 및 그 구성약재의 항균활성에 관한 연구
Antimicrobial Activity of Korean Traditional Prescription (Kumkue-Yoryak) and Herb Simplexes Extracts to Vibrio Parahemolyticus
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Ma, Jin-Yeul
(Korea Institute of Oriental Medicine) ;
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Kim, Jin-Sook
(Korea Institute of Oriental Medicine) ;
- Jung, Kyu-Yong (Wonkwang University Medical school Pharmacology) ;
- Park, Kap-Joo (Konkuk University Department of Biology)
- 발행 : 2000.04.30
초록
Vibrio become prevailing if superficial temperature of ocean is raised and their activities of area are expanded and most of ocean creatures(fishes, oysters etc) are polluted with vibrio. The one who has taken these polluted fishes and oysters uncooked caused foodpoisoning and diarrhea from Vibrio. Frequently these diseases breakout is disposed in westsea shore of Korea. According to ancient and traditional Korean medical book - Kumkue Yorak - and their single, we carried out experiment check the activities of natural medicinal effects on Vibrio parahemolyticus. The prescriptions of trial materials are processed from extraction boiling water and 80% methanol and followed by freeze dried and adsorbed to every discs in dosage of 10mg. Gentamycin of 10mg were used for control. The result of compound prescription displayed special diseases in antimicrobial activities of boiling water and MeOH extraction compared with control. In single prescription, extraction of boiling water and MeOH of Schisandra sphenanthera(clear zone : 15mm) presented extraordinal antimicrobial activity. The MBC of Schisandra sphenanthera extracts was expressed 2.56mg/ml in boiling water and MeOH.
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