Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Unknown Squamous Cell Carcinoma Incidentally Found in the Thrombus After Pulmonary Embolectomy

폐색전 제거술 후 혈전에서 우연히 확인된 원발 미상 편평 상피 세포암 1예

  • Choi, Chang-Hwan (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Park, Young-Soo (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Ryu, Dong-Ryeol (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Park, Sung-Ha (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Ko, Won-Ki (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Ahn, Kang-Hyun (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Park, Jae-Min (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Kim, Se-Kyu (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Chang, Joon (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Kim, Sung-Kyu (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases) ;
  • Lee, Won-Young (Department of Internal Medicine, Yonsei University College of Medicine, The Institute of Chest Diseases)
  • 최창환 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 박영수 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 류동렬 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 박성하 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 고원기 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 안강현 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 박재민 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 김세규 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 장준 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 김성규 (연세대학교 의과대학 내과학교실, 폐질환 연구소) ;
  • 이원영 (연세대학교 의과대학 내과학교실, 폐질환 연구소)
  • Published : 1999.07.30
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Abstract

A thromboembolic event in patients later given a diagnosis of cancer is the result rather than the cause of the cancer. The risk of hidden cancer is significantly higher for patients with recurrent idiopathic thromboembolism compared to those with secondary deep vein thrombosis. Microemboli from hepatic or adrenal metastases and large-sized emboli from the great veins invaded by the tumor are the sources of tumor embolization The intraarterial tumor emboli less likely invade the arterial wall. Thrombus formation and organization may be capable of destroying tumor cells within pulmorlary blood vessels. Therefore, all tumor emboli are not true metastases. The treatment of deep vein thrombosis and pulmonary embolism in patients with cancer consists of anticoagulation with heparin and warfarin, venacaval filters, appropriate anti-neoplastic agents, and surgical methods(embolectomy, thromboendarterectomy). However, considerable literatures suggest that oral anticoagulant such as warfarin is ineffective in the treatment of those. We report a case of primary unknown squamous cell carcinoma incidentally found in the thrombus after pulmonary embolectomy.

저자 등은 폐색전증이 확인된 환자에서 지속적인 경구 warfarin 항응고 치료에도 불구하고 색전에 의한 호흡곤란 증상이 악화하여 시행한 색전제거술 후 혈전에서 원발 미상의 미분화 편평 상피 세포암이 확인된 1예를 경험하여 보고하는 바이다.

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