Journal of Applied Biological Chemistry
- Volume 42 Issue 2
- /
- Pages.97-99
- /
- 1999
- /
- 1976-0442(pISSN)
- /
- 2234-7941(eISSN)
Screening of Taxol-producing Endophytic Fungi from Ginkgo biloba and Taxus cuspidata in Korea
- Kim, Soo-Un (Division of Applied Biology and Chemistry, and The Research Center for New Biomaterials in Agriculture, Seoul National University) ;
- Strobel, Gary (Department of Plant Pathology, Montana State University) ;
- Ford, Eugene (Department of Plant Pathology, Montana State University)
- Received : 1999.05.31
- Published : 1999.06.30
Abstract
Endophytic fungi from Ginkgo biloba and Taxus cuspidata in Korea were screened for production of taxol. Eighteen and twelve fungal isolates from G. biloba and T. cuspidata, respectively, were shown to produce immunologically detectable amount of taxol. The highest production of taxol at 260 ng/l was achieved by stationary culture of an Alternaria isolate from G. biloba. The strain also produced unidentified antifungal agent(s) against Pythium ultimum. However, the activity gradually decreased when the strain was stored at