Journal of Food Hygiene and Safety (한국식품위생안전성학회지)
- Volume 14 Issue 2
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- Pages.129-133
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- 1999
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- 1229-1153(pISSN)
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- 2465-9223(eISSN)
Effects of T-2 Toxin on Lipid Concentration in Rat Serum
T-2 toxin이 흰쥐 혈철 중 지질농도에 미치는 영향
Abstract
This study was designed to observe the effects of T-2 toxin on total cholesterol and lipid concentration in rat serum. T-2 toxin is a secondary metabolite produced by Fusarium sp. which is often found on agricultural products including cereals, and it is a causal material of liver injuries in cattle and humans. When we fed rats with standard diet treated with T-2 toxin, the body weight and feed consumption of rats treated T-2 toxin were decreased. As the results of lipid analysis, the concentrations of total cholesterol and free cholesterol in serum of treated rats were increased compared to non-fed control group, On the other hand, the levels of triglyceride and phospholipid in the serum of T-2 toxin treated experimental groups were declined. In conclusion, T-2 toxin largely influenced on the total cholesterol and lipid levels in rat serum.