YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Total Synthesis of Isopimarol Diterpene

Isopimarol Diterpene의 전합성

  • Published : 1999.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

The first and versatile total synthesis of isopimarol diterpene has been achieved via stereoselective construction of C-13 quaternary carbon unit as a key step. Isopimarol diterpene was synthesized from the known decalone in 17% overall yield of 16 steps.

Keywords

References

  1. The Total Synthesis of Natural Products v.3 Apsimon, J.
  2. Arch. Pharm. Res. v.18 An Efficient Synthesis of B,C-ring Moiety of Pimara-diterpenes Isolated from Acanthopanax koreanum Suh, Y.-G.;Park, H.-J.;Jun, L.-O.
  3. Tetrahedron v.54 Practical and Versatile Syntheses of Angular Hydroxymethylated Decalones Suh, Y.-G.;Kim, H.-S.;Kumar, P. Raja;Choi, N.-S.;Jung, J.-K.
  4. Synthetic Communications v.27 Stereoselective Construction of C-13 Quaternary Carbon Unit of Isopimarane Diterpene and Its Synthetic Application to Isopimarol Diterpene Suh, Y.-G.;Jun, R.-O.;Jung, J.-K.;Ryu, J.-S.
  5. Phytochemistry v.29 Diterpenoids from Calceolaria Species 5. Diterpenes from Calceolaria-Lepida Chamy, M. C.;Piovano, M.;Garbarino, J. A.;Miranda, C.;Gambaro, V.
  6. J. Am. Chem. Soc. v.90 A Stereoselective Synthesis of Racemic Andrographolide Lactone Pelletier, S. W.;Chappell, R. L.;Prabhakar, S.
  7. Tetrahedron Lett. v.26 Intramolecular Double Michael Reaction III. Stereoselective Chiral Synthesis of Atisiran-15-one Ihara, M.;Toyota, M.;Fukumoto, K.;Kametani, T.
  8. Tetrahedron Lett. v.24 Regioselective Synthesis of β-Ketoesters from Lithium Enolates and Methyl Cyanoformate Mander, L. N.;Sethi, P.
  9. Asymmetric Synthesis v.3 Morrison, J. D.
  10. J. Am. Chem. Soc. v.103 Lanthanoids in Organic Synthesis 6, The Reduction of α-Enone by Sodium Borohydride in the Presence of Lanthanoid Chloride : synthetic and Mechanistic Aspects Gemal, A. L.;Luche, J. L.
  11. J. Org. Chem. v.54 Allyl Esters as Carboxy Protecting Groups in the Synthesis of O-Glycopeptides Friedrich-Bochnitschek, S.;Waldmann, H.;Kunz, H.