Applied Biological Chemistry

The Korean Society for Applied Biological Chemistry (한국응용생명화학회)
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Effects of Compounds Isolated from Ainsliaea acerifolia on the Hepatic Alcohol Dehydrogenase Activity

단풍취로부터 분리한 Apigenin $7-O-{\beta}-D-glucoside$가 알콜대사효소에 미치는 영향

  • Zee, Ok-Pyo (Pharmacognocy Lab, Department of Pharmacy, Sungkyunkwan University) ;
  • Shin, Mal-Shick (Department of Food and Nutrition, Chonnam National University) ;
  • Moon, Hyung-In (Pharmacognocy Lab, Department of Pharmacy, Sungkyunkwan University)
  • 지옥표 (성균관대학교 약학대학 생약학연구실) ;
  • 신말식 (전남대학교 식품영양학과) ;
  • 문형인 (성균관대학교 약학대학 생약학연구실)
  • Published : 1999.05.31
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Abstract

Effects of compounds isolated from Ainsliaea acerifolia on alcohol metabolism in rats were examined and the results were as follows: Apigenin $7-O-{\beta}-D-glucoside$, after a single oral administration to rats, was found to cause a significant decrease in the serum ethanol concentration as well as enhancement of liver cytosolic alcohol dehydrogenase(ADH) activity.

Spraque-Dawley계 수컷랫트에 단풍취로부터 분리한 화합물을 경구투여하고 혈청 ethanol농도와 간의 ADH 활성에 미치는 효과를 검토한 결과 알코올대사를 촉진시키는 성분은 apigenin $7-O-{\beta}-D-glucoside$로 확인되었다.

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