생약학회지 (Korean Journal of Pharmacognosy)

  • 제30권2호
  • /
  • Pages.196-201
  • /
  • 1999
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

고추나물의 항산화 활성 Flavonoid 성분

Antioxidative Flavonoids from Hypericum erectum

  • 정칠만 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 황은주 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 권학철 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 김선여 (농촌 친흥청 농업과학기술원) ;
  • 배기환 (충남대학교 약학대학) ;
  • 지옥표 (성균관대학교 약학대학 천연물약품화학연구실) ;
  • 이강노 (성균관대학교 약학대학 천연물약품화학연구실)
  • Jung, Chil-Man (College of Pharmacy, Sung Kyun Kwan University) ;
  • Hwang, Eun-Ju (College of Pharmacy, Sung Kyun Kwan University) ;
  • Kwon, Hak-Chul (College of Pharmacy, Sung Kyun Kwan University) ;
  • Kim, Sun-Yeou (Dept. of Sericulture & Entomology, National Institute Agricultural Science and Technology, RDA) ;
  • Bae, Ki-Hwan (College of Pharmacy, Chungnam National University) ;
  • Zee, Ok-Pyo (College of Pharmacy, Sung Kyun Kwan University) ;
  • Lee, Kang-Ro (College of Pharmacy, Sung Kyun Kwan University)
  • 발행 : 1999.06.30
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초록

Four antioxidative flavonoids were isolated from the aerial parts of Hypericum erectum. Their structures were identified as quercitrin (I), isoquercitrin (Ⅱ), hyperoside (Ⅲ) and orientin (IV) on the basis of spectroscopic means. Antioxidative activities for flavonoids $I{\sim}IV$ were determined by measuring lipid peroxide using 2-thiobarbituric acid (TBA) method and by evaluation the radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. Compound IV, orientin, was found to have strong antioxidative potency.

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