The Korean Journal of Physiology and Pharmacology
- Volume 3 Issue 2
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- Pages.223-230
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- 1999
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- 1226-4512(pISSN)
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- 2093-3827(eISSN)
Thyroid Hormone-Induced Alterations of $Ca^{2+}-ATPase$ and Phospholamban Protein Expression in Cardiac Sarcoplasmic Reticulum
- Kim, Hae-Won (Department of Pharmacology, University of Ulsan College of Medicine) ;
- Noh, Kyung-Min (Department of Pharmacology, University of Ulsan College of Medicine) ;
- Park, Mi-Young (Department of Pharmacology, University of Ulsan College of Medicine) ;
- Lee, Hee-Ran (Asan Institute for Life Science) ;
- Lee, Eun-Hee (Department of Pharmacology, University of Ulsan College of Medicine)
- Published : 1999.04.21
Abstract
Alterations of cardiovascular function associated with various thyroid states have been studied. In hyperthyroidism left ventricular contractility and relaxation velocity were increased, whereas these parameters were decreased in hypothyroidism. The mechanisms for these changes have been suggested to include alterations in the expression and/or activity levels of various proteins;