한국환경성돌연변이발암원학회지 (Environmental Mutagens and Carcinogens)
- 제18권1호
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- Pages.22-25
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- 1998
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- 1225-6307(pISSN)
DMBA로 유발한 Mouse 피부암에 대한 Astaxanthin이 함유된 난황의 항암효과
Inhibition of DMBA-Induced Mouse Epidermal Carcinogenesis by Astaxanthin-Containing Egg Yolks
- 이상호 (해태제과 중앙연구소) ;
- 박철우 (경상대학교 농화학과) ;
- 이영춘 (중앙대학교 식품공학과) ;
-
최의성
(생명공학연구소 응용미생물연구부) ;
- 김무남 (경상대학교 농화학과) ;
-
하영래
(경상대학교 농화학과)
- Lee, Sang-Ho (Institute of Hatai Confectionary Co., LTD) ;
- Park, Cheol-U (Department of Agricultural Chemistry, Gyeongsang National University) ;
- Lee, Yeong-Chun (Department of Food Technology, Chungang University) ;
-
Choe, Ui-Seong
(Applied Microbiology Research Division, Korea Research Institute of Bioscience & Biotechnology (KRIBB)) ;
- Kim, Mu-Nam (Department of Agricultural Chemistry, Gyeongsang National University) ;
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Ha, Yeong-Rae
(Department of Agricultural Chemistry, Gyeongsang National University)
- 발행 : 1998.03.01
초록
Anticarcinogenic activity of astaxanthin-containing egg yolks (designate AEY) was investigated for 7,12-dimethylbenz[a]anthracene (DMBA)-induced two stage mouse epidermal carcinogenesis. Female ICR mouse (6-7 weeks of age) were house in a humidity-and-temperature-controlled facility and subjected to feed and water ad libitum. AEY (10 mg/0.2 ml acetone) was painted on the back of mice 7 days, 3 days and 5 min before DMBA treatment (50 nmole/0.2 ml acetone). One week later after DMBA treatment, 6