The Journal of Korean Society of Virology (대한바이러스학회지)

The Korean Society of Virology (대한바이러스학회)
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Seroepidemiologic Analysis of Acute Febrile Illness from Korea in 1996

1996년 한국에서 발생한 열성질환에 대한 혈청역학적 연구

  • Song, Jin-Won (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Han, Sung-Hee (Graduate School, Korea University) ;
  • Baek, Luck-Ju (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Lee, Yong-Ju (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University) ;
  • Song, Ki-Joon (Department of Microbiology, College of Medicine, Institute for Viral Diseases, Korea University)
  • 송진원 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 한성희 (고려대학교 대학원) ;
  • 백락주 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 이용주 (고려대학교 의과대학 미생물학교실, 바이러스병연구소) ;
  • 송기준 (고려대학교 의과대학 미생물학교실, 바이러스병연구소)
  • Published : 1998.12.30
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Abstract

Hemorrhagic fever with renal syndrome (HFRS), scrub typhus, murine typhus and leptospirosis have been the principal acute febrile diseases in Korea. To evaluate the seroepidemiologic patterns of acute febrile illness, sera collected from 2,423 patients in 1996 were examined for antibodies against Hantaan virus, Orientia tsutsugamushi, Rickettsia typhi, and Borrelia burgdorferi by indirect immunofluorescent antibody technique (IFA) and macroscopic agglutination test for Leptospira interogans. Seropositive cases against Otsutsugamushi, Rickettsia typhi, Leptospira interogans and Hantaan virus were 192 (7.9%), 193 (8.0%), 12 (0.5%) and 324 (13.4%), respectively. Male was more affected in HFRS and murine typhus contrasting to scrub typhus and leptospirosis in female. Most positive cases occurred during October and November for scrub typhus, and during November and December for HFRS. These results showed similar patterns with previous epidemical data for recent couple of years, and possibly implied no significant changes occurred in ecologic situations for acute febrile diseases in Korea.

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