Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Histological and Immunohistological Studies of the Thyroid Glands of the Osteoporotic Rats Induced by Ovariectomy

난소절제로 유발된 골다공증 시 흰쥐 갑상샘에 대한 조직학적 및 면역조직화학적 연구

  • 김대영 (경북대학교 수의과대학) ;
  • 구세광 (경북대학교 수의과대학) ;
  • 이재현 (경북대학교 수의과대학) ;
  • 장인호 (경북대학교 수의과대학) ;
  • 이형식 (경산대학교 자연과학대학 생물학과)
  • Published : 1998.06.01
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Abstract

In order to investigate the histological and immunohistochemical changes of thyroid glands, and serum osteocalcini estradiol, pmgesterone, follicular-stimulating hormone (FSH), and calcium levels in the osteoporotic rats induced by ovariectomy, normal(sham-operated group) and experimental groups(ovariectomized group) were divided. The experimental groups were subdivide6 to 5, 10, 15, and 20 weeks after ovariectomized groups. The histological structure of the thyroid gland were observed in normal structure throughout all experimental periods but the calcitonin-immunoreartive cells in the experimental groups were significantly decreased compared with normal groups and degranulations of calcitonin-immunoreactive cells were observed. Theses numbers were decreased with time after ovariectomy. However, the serum osteocalcin and FSH levels of experimental groups were significantly increased compared with normal groups and these levels were increased along with time after ovariectomy, but serum estradiol, progestemn and calcium levels of experimental group were significantly decreased compared with normal groups and these levels were decreased with time after ovariectomy.

Keywords

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