Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Studies on the Anti-inflammatory Effects of Drymaria cordata Willd

  • Mukherjee, Pulok K. (JSS College of Pharmacy) ;
  • Mukherjee, Kakali (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur Uniersity) ;
  • Bhattacharya, S. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Pal, M. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University) ;
  • Saha, B.P. (Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University)
  • Published : 1998.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

In folklore medicine Drymaria cordata Willd (Family-Caryophyllaceae) is reported to have laxative and anti-febrile properties along with anti-inflammatory activities. Sikkimis used this plant to treat all these ailments. The anti-inflammatory effect of the methanol extract of D. cordata was investigated against carrageenin, histamine, serotonin, dextran and $PGE_1$ induced rat hind paw oedema. It exhibited significant anti-inflammatory activity against all these phlogestic agents except $PGE_1$ in the order of carrageenin > serotonin > histamine. All these effects were compared with standard drug phenylbutazone in both the acute and chronic experimental models in albino rats.

Keywords