Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Studies on the Chemical Composition and Antitumor Activity of the Acid Polysaccharide from Alga Sargassum fusiforme

  • Qianqun, Gu (Institute of Marine Drugs and Foods, Oean University of Qingdao) ;
  • Yuchun, Fang (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
  • Changyun, Wang (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
  • Bafang, Li (Institute of Marine Drugs and Foods, Ocean University of Qingdao) ;
  • Wenjun, Mao (Institute of Marine Drugs and Foods, Ocean University of Qingdao)
  • Published : 1998.06.01
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Abstract

An acid polysaccharide (SFP), was extracted from alga Sargassum fusiforme in hot water, was purified by ion exchange chromatography on DEAE-cellulose. The PC, chemical analysis, electrophoresis and IR of SFP indicated that it was a kind of alginate with a mol. wt. of 13,000 and a molar ratio of mannuronic acid to guluronic acid 2.75. Pharmacological tests showed that SFP could prolong the survival duration of mice suffering from ascitic Sarcoma 180 with a rate of life prolongation of 63.44%.

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