Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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Separation of EPA and DHA from Fatty Acid of Fish Oil by Urea Adduct Formation Using Supercritical Carbon Dioxide Solvent

초임계 이산화탄소 용매하의 요소부가법에 의한 어유지방산으로부터 EPA와 DHA의 분리

  • Kim, Jae-Duck (CFC Alternatives Technology Center, Korea Institute of Science and Technology) ;
  • Lim, Jong-Sung (CFC Alternatives Technology Center, Korea Institute of Science and Technology) ;
  • Lee, Youn-Woo (CFC Alternatives Technology Center, Korea Institute of Science and Technology)
  • 김재덕 (한국과학기술연구원 CFC대체기술센터) ;
  • 임종성 (한국과학기술연구원 CFC대체기술센터) ;
  • 이윤우 (한국과학기술연구원 CFC대체기술센터)
  • Published : 1997.08.31
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Abstract

Separation of EPA and DHA from fish oil fatty acid ethyl ester (FAFE) by urea adductive crystallization method was carried out in the supercritical carbon dioxide (SC $CO_2$) as a solvent. Our results showed that SC $CO_2$ is a good candidate as a solvent in the urea adductive crystallization to separate FAFE by the number of unsaturated bonds. Compared to the separation process using methanol. SC $CO_2$ yielded better performance in the overall selectivity of EPA and DHA. The effect of process variables on separation of EPA and DHA was discussed in detailed. A hybrid technology of SC $CO_2$ fractionation and urea adductive crystallization with SC $CO_2$ was conformed as a viable process to separate and concentrate EPA and DHA from fish oil.

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