Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Effects of Administration of CCl$_{4}$ on Liver Function in Rats 1. Clinical Signs and Blood Chemical Values

사염화탄소(CCI$_{4}$)의 투여가 쥐의 간기능에 미치는 영향 1. 임상증상 및 혈액화학치

  • 강정부 (경상대학교 수의과대학(동물의학 연구소)) ;
  • 이은석 (마산 창생동물병원) ;
  • 허주헝 (부평 고려동물병원)
  • Published : 1997.06.01
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Abstract

This study was performed to estimate the clinical signs and biochemical para meters of indicator on acute hepatic injury induced by the administration of CCl$_{4}$ in rats. Minor behavioral changer brittleness of skin hair and decreased volume of water and food intake were observed in rats after 2 hours of $CCl_{4}$ administration compared to control group. Concentration of serum albumin has shown lower than that of control group. However concentration of total bilirubin has shown higher than that of control group. As times go onto serum LDH activity was significantly increased compared to control Broup. Serum CPK activity hasn't shown change compared to control group. Passive hemagglutination that of afetoprotein was shown negative reaction in all the treatment groups and control group.

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