한국균학회지 (The Korean Journal of Mycology)

한국균학회 (The Korean Society of Mycology)
권호 표지

버섯중 항균활성물질의 개발 -버섯중의 식물병원성 곰팡이에 대한 항균활성 물질 검색-

Development of Antibiotics in Mushroom -The Screening of Antifungal Activities in Basidiomycetes-

  • 민지영 (동국대학교 생명자원과학대학 응용생물학과) ;
  • 김은미 (동국대학교 생명자원과학대학 응용생물학과) ;
  • 민태진 (동국대학교 이과대학 화학과)
  • Min, Ji-Young (Department of Applied Biology, Dongguk University) ;
  • Kim, Eun-Mi (Department of Applied Biology, Dongguk University) ;
  • Min, Tae-Jin (Department of Chemistry, Dongguk University)
  • 발행 : 1997.12.30
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초록

한국산 흰주름버섯외 50종 버섯을 채집하여 석유에테르, 80%에탄올 및 멸균증류수로 각각 추출하여 153종의 추출물을 얻어 식물병원성 곰팡이에 대한 항균활성을 검색하였다. A. alternata에 항균활성은 독우산광대버섯의 물 추출물, MPC-3 버섯의 에탄올 추출물 그리고 큰낙엽버섯과 Xanthoconium affine의 석유에테르 추출물이 활성을 보였다. 잔디탄저병균, C. graminicola에 대하여는 애광대버섯, 노란길민그물버섯 그리고 흰둘레무당버섯의 석유에테르 추출물이, 해면버섯, MPC-3 버섯 그리고 주걱송편버섯의 에탄올 추출물이, 조개껍질 버섯의 물 추출물이 각각 항균활성을 보였다. 인삼뿌리썩음병균, C. destructans에 대하여는 애광대버섯, 수원그물버섯, 해면버섯, MPC-3 버섯, 주걱 송편버섯, 띠미로버섯 그리고 외대덧버섯의 에탄올 추출물이, 애광대버섯, 흰둘레무당버섯, 향버섯, 큰낙엽버섯의 석유에테르 추출물이 각각 항균활성을 보였다. 오이덩굴쪼김병균, F. o. cucumerinum에 대하여는 MPC-3 버섯의 에탄올 추출물이 항균활성을 보였다. 감자시들음병균, F. solani에 대하여는 진갈색주름버섯의 물 추출물이 그리고 무변색무당버섯의 에탄올 추출물이 각각 항균활성을 보였다. 잔디탄저병균, I. bolleyte에 대하여는 진갈색주름버섯의 물 추출물이 그리고 MPC-3버섯의 에탄올 추출물이 각각 항균활성을 보였다.

The antifungal activities of 153 extracts from 51 species of Korean mushroom on six phytopathogenic fungi were investigated. The powder of fruit-body of each mushroom was extracted with petroleum ether, 80% ethanol and distilled water. The water extracts of four mushrooms including Amanita virosa showed antifungal activities on Alternaria alternata, Colletotrichum graminicola, Fusarium solani, Idriella bolleyie. The 80% ethanol extracts of seven mushrooms including Boletus auripes showed antibiotic activities against A. alternata, C. gramincola, Cylindrocarpon destructans, F. solani, F. oxysporum cucumerinum, and I. bolleyie. The petroleum ether extracts of six mushrooms including Amanita citrina showed antibiotic activities against A. alternata, C. destructans, and C. graminicola. The 102 extracts of 34 mushrooms including Agaricus arvensis didn't show antibiotic activities.

키워드

참고문헌

  1. 한국의 버섯 박완희
  2. 新稿 稙物炳理學 박종성
  3. 균학회소식 v.5 no.1 한국산 고등균류 분류학 발표목록 정학성
  4. 식물균병학연구 정후섭
  5. キノコウ化學, 生化學 水野卓;川合正允
  6. 新農本草經. 3卷 吳普(等)(述);孫星衍;孫馬翼(輯)
  7. 嘉慶4年 吳普(等)(述);孫星衍;孫馬翼(輯)
  8. 東醫寶鑑 許浚;東醫寶鑑國譯委員會 (編譯)
  9. Kor. J. Mycol. v.20 no.2 Medicinal Fungi in Korea Abn, D.K.
  10. Can. J. Microbiol. v.17 Cyathin, A New Antibiotic Complex Produced by Cyathus helenae Allbutt, A.D.;Ayer, W.A.;Brodie, H.J.;Johri, B.N.;Taube, H.
  11. J. Antibiotics v.30 no.3 The Striantins-New Antibiotics from the Basidiomycete Cyathus striatus(Huds. ex Pers.) Willd Anke, T.;Oberwinkler, F.
  12. J. Antibiotics v.30 no.10 The Strobilurins New Antifungal Antibiotics from the Basidiomycete Strobilurus tenacellus(Pers. ex Fr.) Sing Anke, T.;Oberwinkler, F.
  13. J. Antibiotics v.32 no.11 Antibiotics from Basidiomycetes. IX, Oudemansin, An Antifungal Antibiotic from Oudemansiella mucida(Schrader ex Fr.) Hoehnel (Agaricales) Anke, T.;Hecht, H.J.;Schramm, G.;Steglich, W.
  14. J. Antibiotics v.33 no.5 Antibiotics from Basidiomycetes. X, Scorodonin, A New Antibacterial and Antifungal Metabolite from Marasmius scorodonius (Fr.) Fr Anke, T.;Kupka, J.;Schramm, G.;Steglich, W.
  15. Am. J. Clin. Pathol. v.45 no.4 Antibiotic susceptibility testing by a standardized single disk method Bauer, A.W.;Kirby, W.M.M.;Sherris, J.C.;Turck, M.
  16. J. Chem. Soc. Chemistry of the Higher Fungi Part XVI, Polyacetylenic Metabolites from Aleurodiscus roseus Cambie, R.C.;Hirschberg, A.;Jones, E.R.H.;Lowe, G.
  17. Rep. Tottori Mycol. Inst.(Japan) v.12 Studies on Cylindrocarpon destructans(Zins.) Scholten causing root rot of ginseng Chung, H.S.
  18. 5th Int. Congr. P1. Pathol. Abstr. Recent advance of studies on rice fungal diseases Chung, H.S.
  19. Difco manual
  20. J. Antibiotics v.45 no.1 Antibiotics from Basidiomycetes XLI, Clavicoronic acid, A Novel Inhibitor of Reverse Transcriptases from Clavicorona pyxidata(Pers. ex Fr.) Doty Erkel, G.;Anke, T.
  21. J. Antibiotics v.40 no.2 6-Deoxyilludin M, A New Antitumor Antibiotic: Fermentation, Isolation and Structural Identification Hara, M.;Yoshida, M.;Morimoto, M.;Nakano, H.
  22. J. Antibiotics v.41 no.12 Antibiotics from Basidiomycetes. XXIX: Pilatin, A New Antibiotically Active Marasmane Derivative from Cultures of Flagelloscypha pilatii Agerer Heim, J.;Anke, T.
  23. Science v.235 Signaling for growth orientation and cell differentiation by surface topography in Uromyces Hoch, H.C.;Staples, R.C.;Whitehead, B.;Comeau, J.;Wolf, E.D.
  24. J. Antibiotics v.36 no.4 Basidalin, A New Antibiotic from Basidiomycetes linuma, H.;Nakamura, H.;Naganawa, H.;Masuda,T.;Takano, S.;Takeuchi, T.;Umezawa, H.;Iitaka, Y.;Obayashi, A.
  25. Korean J. Plant Pathol. v.9 no.1 Significant attribute biocontrol agent for colonizing ability at corresponding-infection site of soil-borne plant pathogens Jang, S.S.;Jeong, M.J.;Park, C.S.;Kim, H.K.
  26. J. Chern. Soc. Chemistry of the Higher Fungi. Part XIII, Synthesis of (a) a $C_9$ Triacetylenic Epoxy-alcohol, a Coprinus quadrifidus Metabolite and (b) a $C_9$ Triacetylenic 1,2-Dio1. The Structure of Biformyne 1 Jones, E.R.H.;Stephenson, J.S.;Turner, W.B.;Whiting, M.C.
  27. Pro. Natl. Acad. Sci. USA v.35 Antibiotic substances from basidiomycetes. IV. Marasmius conigenus Kavanagh, F.;Hervey, A.;Robbins, W.J.
  28. J. Am. Chem. Soc. v.89 no.5 The Structure of Fomannosin, a Novel Sesquiter-pene Metabolite of the Fungus Fomes annosus Kepler, J.A.;Wall, M.E.;Mason, J.E.;Basset, C.;McPhail, A.T.;Sim, G.A.
  29. J. Antibiotics v.39 no.4 Structure of New Antibiotics, Pereniporins A and B, from a Basidiomycete Kida, T.;Shibai, H.;Seto, H.
  30. Kor. J. Mycol. v.24 no.3 Two phenolic compounds Isolated from Umbilicaria esculenta as Phospholipase $A_2$ Inhibitors Kim, J.W.;Song, K.S.;Yoo, I.D.;Chang, H.W.;Yu, S.H.;Bae, K.G.;Min, T.J.
  31. Diagnostic Microbiol Koneman, E.W.;Allen, S.D.;Janda, W.M.;Schreckenberger, P.C.;Winn, W.C.
  32. Pat. J. Antibiotics v.32 no.2 Antibiotics from Basidiomycetes. VII. Crinipellin, A New Antibiotic from the Basidiomycetous Fungus Crinipellis stipitaria(Fr.) Kupka, J.;Anke, T.;Oberwinkler, F.
  33. Trans. Br. Mycol. Soc. v.70 Location of appressoria of Colletotrichum graminicola on natural and artificial barley leaf surfaces Lapp, M.S.;Skoropad, W.P.
  34. Kor. J. Mycol. v.23 no.1 Studies on the Screening and Development of Antibiotics in the Mushroom- The Screening of Fungal Antibiotics in Basidiomycetes (1) Lee, K.D.;Su, Y.C.;Park, S.S.;Min, T. J.
  35. Kor. J. Mycol. v.18 no.4 The Full List of Recorded Mushroom in Korea Lee, T.S.
  36. Tetrahedron Left. v.23 Melleolide, A New Antibiotic from Armillaria mellea Midland, S.L.;Izac, R.R.;Wing, R.M.;Zaki, A.I.;Munnecke, D.E.;Sims, J.J.
  37. Kor. J. Mycol. v.23 no.1 Studies on the Screening and Development of Antibiotics in the Mushroom- The Screening of Antifungal Components in Basidiomycetes(I) Min, T.J.;Kim, E.M.;Lee, S.J.;Bae, K.G.
  38. J. Korean Chem. Soc. v.40 no.9 The Structure of Phenolic Compounds and Their Antibiotic Activities in Umbilicaria vellea Min, T.J.;Bae, K.G.
  39. Kor. J. Mycol. v.24 no.1 The Screening of Antifungal Activities of Extracts from Mushrooms in Korea(II) Min, T.J.;Kim, E.M.;You, S.H.
  40. Soil biology and biochemistry v.5 The Mechanisms of Biological Control of Plant Disease Mitchell, J.E.
  41. Kor. J. Mycol. v.23 no.1 Studies on the Screening and Development of Antibiotics in the Mushroom- The Screening of Bacterial Antibiotics in Basidiomycetes(l) Park, S.S.;Lee, K.D.;Min, T.J.
  42. Kor. J. Mycol. v.23 no.1 Studies on the Screening and Development of Antibiotics in the Mushroom- The Screening of Bacterial and Fungal Antibiotics in Basidiomycetes(II) Park, S.S.;Lee, K.D.;Min, T.J.
  43. J. Antibiotics v.31 no.8 Antibiotics from Basidiomycetes. V, Merulidial A New Antibiotic from the Basidiomycete Merulius tremellosus Fr Quack, W.;Anke, T.;Oberwinkler, F.
  44. Compendium of turf grass disease Flsmiley, Richard W.;Bernoeden, Peter H.;Clarke, Bruce B.
  45. Chem. Pharm. Bull. v.36 no.7 The Constituents of Lactarius flavidulus Imai Takahashi, A.;Kusano, G.;Ohta, T.;Nozoe, S.
  46. J. Antibiotics v.28 no.1 A New Antibiotic, Calvatic acid Umezawa, H.;Takeuchi, T.;Iinuma, H.;Ito, M.;Ishizuka, M.;Kurakata, Y.;Umeda, Y.;Nakanish, Y.;Nakamura, T.;Obayashi, A.;Tanabe, O.
  47. Antibiotics in Lab. Med Victor Lorian, M.D.C.
  48. Kor. J. Mycol. v.23 no.1 An Antibacterial Lectin from Lampteromyces japonicus Yoon, J.O.;Min, T.J.;Yoon, H.S.